Transcription activator proteins bind to [{Blank}] on DNA. What is transcription? Describe the process of transcription. Where does it occur? What enzyme(s) are involved? What is the product(s)? What are the transcription start and stop signals in eukaryotes and prokaryote...
Abnormal tumor microenvironment and immune escape in multiple myeloma (MM) are associated with regulatory T cells (Tregs), which play an important role in maintaining self-tolerance and regulating the overall immune response to infection or tumor cells.
Enzymes or complexes that alter nucleosomal positions, composition, conformation or presence using ATP hydrolysis, which enables changes in the accessibility of DNA to other molecules. CREB-binding protein (CBP). Transcriptional activator that couples chromatin remodelling to transcription factor recognition....
At anaphase NuMA is dephosphorylated and can bind to the cortex independently of LGN. This may or may not occur through interaction with Band 4.1 protein(s). The pathway just described explains how cortical proteins can affect spindle orientation. Recent work also suggests that spindle orientation...
activator inhibition c. diffusional regulation d. enzyme activation What type of digestion uses movements and muscles to break down food? When a substrate molecule slips into an active site, the active site changes shape slightly to grip the substrate and catalyze the reaction. What is this ...
epigenetic modifications—such as acetylation, methylation, succinylation, β-hydroxybutyrylation, and lactylation—depend on metabolites. Conversely, epigenetic modifications can regulate the enzymes and proteins involved in metabolism. What roles do these modifications play in the development of renal ...
The proteasome plays an important role in the regulation of a variety of signaling pathways and the degradation of proteins. The proliferation of myeloma cells is dependent on proteasome-regulated signaling pathways, and thus they are susceptible to PIs [118]. PIs can selectively bind to the activ...
In most NCL diseases the storage material consists mainly of subunit c of ATP synthase, while in infantile CLN1 and congenital CLN10 diseases the main components of storage material are sphingolipid activator proteins (SAPs) A and D [28], [29]. Examining the possible implications of PPT1 in...
Despite recent major advances in developing effective vaccines against toxoplasmosis, finding new protective vaccination strategies remains a challenging and elusive goal as it is critical to prevent the disease. Over the past few years, various experimental approaches have shown that developing an effectiv...
(b) How do multiple transcription factors interact to result in the activation of transcription for a particular gene? Which between the the mediator or activator protein is used to assemble chromatin remodeling proteins and transcription factors? What are transcription factors? What is...