Graft versus host disease, or GVHD, is a complication of a stem cell transplant, a treatment for blood cancers and certain blood or immune system disorders. With GVHD, white blood cells called T cells from the donor -- the graft, or the “G” in GVHD -- attack cells within the recipie...
Apremilast, trade name Otezla, etc., is an analogue of thalidomide and is a drug used to treat certain types of psoriasis and psoriatic arthritis. It may also be used in other immune system-related inflammatory diseases. The drug acts as a selective inhibitor of phosphodiesterase 4 (PDE4) an...
Thalidomide: the tragedy of birth defects and the effective treatment of disease. Toxicol Sci. 2011;122(1):1–6. https://doi.org/10.1093/toxsci/kfr088. Article CAS PubMed Google Scholar Matthews SJ, McCoy C. Thalidomide: a review of approved and investigational uses. Clin Ther. 2003;25...
Is Amazon actually giving you a competitive price? This little known plugin reveals the answer. Fatigue and bone pain are usually the first symptoms of multiple myeloma. You may also hear this condition called plasma cell myeloma, MM (for Multiple Myeloma), or Kahler's disease. In all cases,...
Is Autism a Disease or a Disorder? Autism is a disorder, not a disease. There are many brain disorders that fall into the autism category such as autistic disorder, childhood disintegrative disorder, pervasive developmental disorder-not otherwise specified, and Asperger syndrome (Asperger's syndrome...
Is Autism a Disease or a Disorder? Autism is a disorder, not a disease. There are many brain disorders that fall into the autism category such as autistic disorder, childhood disintegrative disorder, pervasive developmental disorder-not otherwise specified, and Asperger syndrome (Asperger's syndrome...
Studies have shown that prenatal exposure to certain drugs and chemicals can affect brain development and increase the risk of autism. For example, when taken during pregnancy, thalidomide (used to treat patients diagnosed with multiple myelomas) and valproic acid (used to treat mania symptoms, sei...
Thalidomide:for severe canker sores and mucocutaneous lesions of Behçet syndrome and for oral ulcers inHIVpatients Apremilast:helps inhibit production of proinflammatory cytokines Montelukast:may relieve pain and improve healing of oral ulcers Cyclosporine:used to treat mucocutaneous ulcers in patients with...
identified by other family members (Olitsky2010; Faughnan et al.2011; Shovlin et al.2000). Given the potentially severe consequences of failure to recognizing this disease early on, it is crucial to appropriately screen patients with suspicious clinical manifestations and intervene prophylactically as...
(IL-1) and tumor necrosis factor-alpha, can greatly benefit people suffering from chronic inflammatory conditions. For instance, azathioprine, 6-mercaptopurine, cyclosporine, and tacrolimus may be used to maintainremissionin Crohn's disease and ulcerativecolitispatients. Azathioprine, cyclophosphamide,...