This is a chronic form of depression, formerly known as dysthymia. Sometimes people call it “high functioning” or “smiling” depression. While symptoms aren’t as severe as MDD, they last fortwo years or longer. People with PDD might feel like they’ve always been depressed. (In cases o...
“All medications have some level of side effects associated with them. It is no different with Lexapro. A commonly reported symptom is weight gain. This can be due to a multitude of reasons but it does exist. Managing the possibility of weight gain through adjustments in exercise and diet w...
Monoamine oxidase inhibitors (MAOIs).Another older class of antidepressants, MAOI medications are rarely used today due to their significant risk of causing side effects and interactions. However, they may be used if other medications aren’t effective. Serotonin-norepinephrine reuptake inhibitors (SNRI...
I have a patient taking the following drugs: aripiprazole, trazodone, sertraline, and simvastatin. Are there any potential drug-drug interactions with this combination of medications? Response from Joel W. Lamoure, RPh, BSP, FASCP Assistant Professor and Assistant CME Director, Schulich School of...
The identified patients (N = 5,012) were predominantly female (65.2%) with a mean age of 41.9 years. The most frequent index SSRIs were citalopram (30.1%) and sertraline (27.5%), and 52.9% of patients were prescribed a second-step pharmacotherapy during the post-index period. Add-on...
Caenorhabditis elegans is a useful model for anthelmintic discovery Article Open access 25 June 2015 Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release Article Open access 24 August 2022 Sertraline, Paroxetine, and Chlor...
The identified patients (N = 5,012) were predominantly female (65.2%) with a mean age of 41.9 years. The most frequent index SSRIs were citalopram (30.1%) and sertraline (27.5%), and 52.9% of patients were prescribed a second-step pharmacotherapy during the post-index period. Add-on...
found elevated serum levels of IL-12, which decreased after eight weeks of sertraline therapy [120]. A recent 2019 study presented a similar picture. Nowak et al. found that patients with MDD without any comorbidities had higher plasma levels of IL-12, which can be mitigated by a sub-...