You might take a biologic alone or with another arthritis drug. As a general rule, you shouldn't take different biologic therapies at the same time. Abatacept (Orencia). This medication is a selective co-stimulation modulator. It works by blocking T cells. You get it in a shot every week...
Systemic lupus erythematosus (SLE) is an autoimmune disease that produces large amounts of immune complexes and autoantibodies and causes damage to the kidneys, skin, joints, and central nervous system. Current SLE treatment is mostly glucocorticoid-led drug therapy, which has more toxic side effects...
Switching from one anti-TNF-α agent to a second (or even third) anti-TNF-α therapy has emerged as a means of addressing treatment failures with this drug class. This review examines data addressing the practice of switching anti-TNF-α agents in the context of initial treatment failure, ...
This latter category, off-label drug use, refers to the use of a drug approved for one indication but used for another indication based on physician discretion, and represents a substantial trend in transplantation. Many drugs established as efficacious in indications such as oncology (e.g. ...
Types of immunotherapies Chimeric antigen receptor (CAR) T cell therapy CAR T-cell therapy is a rapidly emerging class of agents in which a patient’s own cells are collected, engineered to target antigens expressed on malignant cells [10], and re infused (Fig. 1). Currently, approved CAR...