In notch signaling, directcontact between cells allows for precise control of cell differentiation during embryonic development. ... One cell will happen to produce more of a cell surface protein that activates the Notch receptor on the adjacent cell. ...
Th1 cells produce Il-2, IFN-纬, and lymphotoxin; they promote cellular immunity, and are n...Streilein JW. Sunlight and skin-associated lymphoid tissues (SALT): If UVB is the trigger and TNF-alpha is its mediator, what is the message? J Invest Dermatol 1993;100:47S-52S...
Recent years have seen so-called natural killer T (NKT) cells emerge as important regulators of the immune response. The existence of NKT-cell subsets, and other types of T cell that resemble NKT cells, is an ongoing source of confusion in the literature. This perspective article seeks to ...
Defining Sex and Gender Although all cells have a sex, designated by the presence and dosage of X or Y chromosomes, which in most cases will be XX (female) or XY (male), gender is a designated societal determinant and therefore traditionally described only in humans (Bachmann and Mussman,...
produce IL-2 and are highly dependent on exogenous IL-2 [33]. Low dose of IL-2 can promote the expansion of Treg by enhancing the expression of anti-apoptotic protein BCL-2 [34]. Application of IL-2 neutralizing antibody to CD25 can reduce the number of Foxp3+Treg cells and the ...
Activated mast cells produce interleukin 13 J. Exp. Med., 181 (1995), pp. 1373-1380 View in ScopusGoogle Scholar 29. C. Taube, X. Wei, C.H. Swasey, et al. Mast cells, FcepsilonRI, and IL-13 are required for development of airway hyperresponsiveness after aerosolized allergen exposure...
Although all cells have a sex, designated by the presence and dosage of X or Y chromosomes, which in most cases will be XX (female) or XY (male), gender is a designated societal determinant and therefore traditionally described only in humans (Bachmann and Mussman, 2015). Of particular im...
A visual cue is now shown on query result cells that are expandable. Fewer False Positives As with every release, reducing the number of false positives remains a top priority for us: If the same element was declared in several assemblies, its issues were duplicated for each occurrence. Not...
αβ-T cell receptor+ CD4−CD8− T cells produce IL-4. J. Immunol. 149, 1211–1215 (1992). CAS PubMed Google Scholar Sykes, M. Unusual T cell populations in adult murine bone marrow. Prevalence of CD3+CD4−CD8− and αβ TCR+NK1.1+ cells. J. Immunol. 145, 3209–3215 (...
The production of biopharmaceuticals relies on robust cell systems that can produce recombinant proteins at high levels and grow and survive in the stressful bioprocess environment. Chinese hamster ovary cells (CHO) as the main production hosts offer a variety of advantages including robust growth and...