Most people afflicted with the disorder do not live past age 3, though not all deaths are due to the lack of pain. In fact, half of CIPA deaths aredue to overheatingbecause of the person's inability to produce sweat. This causes hyperthermia, or extremely elevated body temperature, which ...
Due to its antiviral and anti-inflammatory properties, HCQ was also tested during the coronavirus disease 2019 (COVID-19) pandemic [15,34], thereby increasing the emergence of rare but life-threatening cases of toxicity, such as pro-arrhythmia possibly leading to sudden cardiac death. By searchi...
Congenital insensitivity to pain with anhidrosis (CIPA) is HSAN type-IV; it occurs due to a mutation in the gene encoding for the neurotrophic tyrosine kinase receptor type I, called the NTRK1 gene[49]. Both pain and cough can be evoked experimentally by stimulating nociceptive C-fibers and...
The sun senses its internal and external systems; it is conscious of them, the number and type of elements it has created, its internal temperatures, its internal plazma flow, its corona and coronal ejections, the gravity of its planets, other objects, and gasses. It senses them and so,...
To study the causes of breast cancer, it could take 30 to 50 years before you know the answer. This is why cancer is an old-age disease. Over 50 percent of all cancers are diagnosed in adults aged 50 to 74. By the time scientists know the answer, you become a statistic. READ PART...
Some say that underarm products like antiperspirants and deodorants with aluminum are unsafe, however, because studies have linked them with breast cancer and Alzheimer's disease [source: Thomas]. Various other factors could cause a change in body odor as well. A diet rich in spicy foods, ...
Interestingly, one study found that the incidence of chronic kidney disease increased in lean individuals with MASLD compared to their non-lean counterparts [45]. Notably, accumulated evidence has shown that overall mortality, of which the other causes apart from liver-related complications included ...
It's a really terrible disease and we are lucky to live in a world where it can basically be cured now. Byirontoenail— On Oct 30, 2013 There was an interesting documentary on people with CIPA recently where they explored what it was like to live in a world where you don't feel pai...