Toll-like receptors (TLRs) have caught the attention of rheumatologists searching for additional therapeutic targets for diseases such as rheumatoid arthritis and systemic lupus erythematosus. Signaling from these molecules can induce the expression of cytokines such as tumor necrosis factor and interferon...
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Toll-like receptors (TLRs) are basic receptors involved in cell signaling in innate immunity. Their exogenous ligands are conserved motifs common for multiple pathogens. The endogenous ligands result from inflammatory processes. TLRs are localized mostly on cells of the innate immune system. There is...
Knockout models of Toll-like receptors (TLR) have demonstrated the critical role that these pattern recognition receptors play in allergic inflammation because loss of TLR2 and TLR4 leads to decreased lower airway inflammation. Mast cell deficient mice are less susceptible to ovalbumin-induced ...
Telephone-based environmental control interventions in asthmatic patients: what are patients willing to do?Telephone-based environmental control interventions in asthmatic patients: what are patients willing to do?Innate immunityToll-like receptorsCD14...
Toll-like receptors: how they work and what they do. The Toll-like receptors are the primary sensors of the innate immune system. This assignment of function was predicated on positional cloning, and was the ... Beutler,Bruce - 《Current Opinion in Hematology》 被引量: 282发表: 2002年 Rev...
Impact of mutations in toll-like receptor pathway genes on esophageal carcinogenesis PLoS Genet., 13 (5) (2017), Article e1006808 CrossrefView in ScopusGoogle Scholar [76] H. Huhta, et al. Toll-like receptors 1, 2, 4 and 6 in esophageal epithelium, Barrett's esophagus, dysplasia and ad...
Many types of innate immune receptor can participate in the immune response but, in virus infections, the most studied are the Toll-like receptors (TLRs), retinoic acid-inducible gene I (RIG-I; also known as DDX58) and NOD-like receptors (NLRs). Virus infections usually activate the ...
Toll-like r... Bochud, Pierre-Yves,M Hersberger,P Taffé,... - 《Aids》 被引量: 253发表: 2007年 Porcine Toll-like receptors: The front line of pathogen monitoring and possible implications for disease resistance Porcine Toll-like receptors: The front line of pathogen monitoring and possible...