1. Intravenous administration: Gemcitabine is rapidly distributed throughout the body after intravenous administration, and becomes active gemcitabine triphosphate under the action of intracellular deoxycytidine kinase to exert anti-tumor effects. Its kinetic parameters are as follows. Gemcitabine is converted ...
Because platelets are crucial in stopping bleeding, signs and symptoms are related to the increased risk of bleeding. If your thrombocytopenia is mild you may not have any symptoms. The lower your platelet count is, the more likely you are to have bleeding. Symptoms include:1 Nosebleeds Bleedin...
Some of them such as CLN1 (palmitoyl protein thioesterase 1), CLN2 (tripeptidyl-peptidase 1), CLN5, CLN10 (cathepsin D), and CLN13 (cathepsin F), are lysosomal soluble proteins; others like CLN3, CLN7, and CLN12, have been proposed to be lysosomal transmembrane proteins. In this ...
When my daughter was born, I almost bled to death, and if was not for someone who gave blood, I probably would not have survived. This is my pay back to the person who gave a part of themselves. I will do this as long as I am able. Thank you whoever you are whose blood saved...
and short term memory, flu-like symptoms, fever, night sweats, tender lymph nodes, sore throat and headache. Word finding problems, reading retention difficulties, ambulation difficulty due to balance problems, felling lightheaded and experiencing and mental fogginess are all symptoms of CFIDS. ...
Biliary colic and cholecystitis are two gallbladder diseases. Biliary colic can lead to cholecystitis if it is not managed properly. Both conditions can be triggered by gallstones. They may have similar symptoms, such as pain in the abdomen and fatigue. ...
For the control group, we included fertile women (with children and no history of recurrent abortion) without clinical symptoms of endometriosis and endometriotic lesions by laparoscopy. 4.4. Characterization and Establishment of the MenSCs In Vitro Model MenSCs. Sample collection. The menstrual blood...
Some are biologically “MGUS-like”, i.e., indolent conditions with a higher tumor burden and in fact one third of SMM patients will never progress in their life. At the other end of the spectrum are “de facto MM” cases, i.e., patients with a biologically aggressive disease, just ...
This fecal microbiota transplant (FMT) from uninjured, non-anxious-like rats not only successfully re-established a healthy microbiota composition after injury, but also improved symptoms of anxiety-like behaviour [2]. Clinically, FMT is defined as the administration of fecal matter solution from a...
In humans, alphaviruses can cause acute infections marked by high viremia and symptoms, including fever, rash, debilitating joint pain, encephalitis, and even morbidity [3,4]. Alphaviruses are arboviruses and are typically disseminated to humans by Aedes aegypti and Aedes albopictus mosquitos. The ...