Functional visceral problems are frequently present nowadays in the medical practice probably due to the significant mental and emotional load on people. Although physicians and psychophysiologists are active on the field, still we are far from a complete knowledge, despite the fact that scientists lik...
The purpose of SOPs today is to guarantee that all workers are performing tasks in the same way, which is a needed for condition to get expected output from the process. When all workers perform their tasks constantly, it becomes possible to run controlled experiments to test the impact of ...
Fluid normally exchanges freely between the plasma and interstitial space and is returned primarily via the lymphatic system. This balance can be disturbed by diseases and medications. In inflammatory disease states, such as sepsis, the return flow of fl
The ethics of clinical research requires equipoise--a state of genuine uncertainty on the part of the clinical investigator regarding the comparative thera... B Freedman - 《N Engl J Med》 被引量: 3307发表: 0年 Placebo-controlled trials in psychiatric research: an ethical perspective The placebo...
If knowledge deficits are identified, further education could address the deficits specifically. Methods This was a cross-sectional study of general pediatricians and registered dietitians in British Columbia (BC). The study was approved by the BC Children's and Women's Behavioural Research Ethics ...
Push incentives include, for example, public investment in research, clinical trials, and support to companies to gain regulatory approvals. ‘Pull’ incentives, meanwhile, are intended to create incentives for companies by, for example, paying pharmaceutical companies for access to a drug, rather ...
Mankind has always relied on “practical wisdom” in the sense of Aristotle to change people and society. However, practical wisdom is difficult to accumulate and pass on from generation to generation. Therefore, although “natural engineering” that is
“…all too often, the risk factors for these disorders are not addressed promptly in clinical practice, leading to irreversible pathologic progression… Traditional approaches to treatment involving sequential therapy, in which agents are added only after one has failed, contribute to clinical inertia ...
Understanding the reasons behind these behaviors is essential for effective implementation of CDSSs. Existing theories on the uptake of information technology and scientific evidence CDSSs are a prime example of a complex healthcare intervention characterized by “a number of components, which may act ...
proven to be safe in other autoimmune conditions, will not have the same safety profile in MS due to immunopathogenetic differences in these diseases (e.g., daclizumab). Identification of SAEs in clinical trials is difficult highlighting the importance of phase IV studies. Memory B cells are ce...