Note. PBE = Present Behavioural Examination; CMAI-C = Cohen-Mansfield Agitation Inventory; CERAD BRSD = Consortium to Establish a Registry for Alzheimer's Disease Behavior Rating Scale for Dementia; BSSD = Behavioral Syndromes Scale for Dementia; NRS = Neurobehavioral Rating Scale. COMMENT The patte...
The ACCORD-2 study met the primary endpoint wherein treatment with AXS-05 statistically and significantly delayed the time to relapse of agitation, as assessed by the Cohen-Mansfield Agitation Inventory (CMAI) total score versus placebo in the given patient population. However, the ADVANCE-2 ...
The ACCORD-2 study met the primary endpoint wherein treatment with AXS-05 statistically and significantly delayed the time to relapse of agitation, as assessed by the Cohen-Mansfield Agitation Inventory (CMAI) total score versus placebo in the given patient population. However, the ADVANCE-2 study...
In two Phase 3, 12-week, placebo-controlled studies, investigators evaluated the frequency of agitation symptoms in patients with dementia due to Alzheimer’s disease based on the Cohen-Mansfield Agitation Inventory (CMAI) total score. The primary endpoint was a change in agitation symptom frequency...
Inc. (CMAI). He acknowledges the "perfect storm" that has hit the resin producers—higher energy costs, higher crude prices, and tighter availability for feedstocks—but notes that the pricing dymanics for PE differ depending on the global region where you happen to reside. "In North America...