Drugs designed to treat diabetes and repurposed as miracle diet aids have taken over TikTok - and Hollywood. The weight loss caused by these weekly injectables is rapid and previously unattainable, people boast, showing off newly svelte bodies. But what are these drugs, how do they...
Repurposed drugs for COVID-19—interim WHO SOLIDARITY trial results. medRxiv.2020. doi:10.1056/NEJMoa2023184 Spinner CD, Gottlieb RL, Criner GJ, et al. Effect of remdesivir vs standard care on clinical status at 11 days in patients with moderate COVID-19: a randomized clinical trial. JAMA...
book reviews,comics,faith,history,nature,parenting,politics,science Selected Book Reviews, October – December 2016 personal,politics,psychology The Problem with Hillary Clinton and the Yankees faith,personal,politics Thou Shalt Not Bear False Witness ...
The most common treatments for migraine are repurposed anti-seizure,blood pressure, antidepressant and immune-modulating medications. Doctors don't know exactly how each medication prevents migraine, but they suspect it involves decreased inflammation, more balanced molecular signaling between neurons, and ...
Effective use of currently available, new, and repurposed drugs, combined with patient-centered treatment that aids adherence and reduces catastrophic costs, are essential. Innovations within sight, such as short, highly effective, broadly indicated regimens, paired with point-of-care drug ...
Hanahan, Dual targeting of the autophagic regulatory circuitry in gliomas with repurposed drugs elicits cell-lethal autophagy and therapeutic benefit. Cancer Cell 28 , 456鈥 471 (2015). [[PubMed] ][1] [1]: http://www.ncbi.nlm... LK Ferrarelli 被引量: 0发表: 2015年 Basic fibroblast...
There is no known treatment for COVID-19 and early clinical trial results of repurposed drugs have so far been disappointing. A trial for hydroxychloroquine—a drug that the US president, Donald Trump, described as a "game changer"—was recentlypaused by the World Health Organization (WHO)for...
graph model enjoys a large ecosystem of tooling, literature, training, a large pool of professionals, and ISO Standards support. By contrast, the RDF community inhabits a world where up-front design of ontologies and standards intended for interoperability on the Web are repurposed as database ...
We funded a number of clinical trials for repurposed drugs. The interim analysis for one of these trials (just completed) suggests that one common generic drug may reduce hospitalization from COVID-19 by about 40%. We expect an announcement here in the near future. ...
So IDO1 inhibitors—originally designed to treat cancers such as melanoma, leukemia and breast cancer—could be repurposed to reduce kynurenine and improve brain function. Using a range of lab models, including mice and cells from Alzheimer's patients, we also found that IDO1 inhibitors can ...