Interactions between proinflammatory cytokines and the innate immune response in ESRD patients; Host responses to bacteremia or endotoxemia.doi:10.1046/j.1525-139x.2000.00044-5.xJ BergstrmB LindholmE LacsonW OwenJ ZimmermannSeminars in Dialysis...
beyond weight control [101]. Indeed, there are many drugs in the pipeline that are considered good candidates for curing NAFLD/NASH, as reviewed previously [102]. In addition to the key role of cytokines, IL-22 activates the JAK1/signal transducer and...
IL-10 inhibits the production of proinflammatory cytokines by target cells through activation of JAK-STAT signaling pathway and acts on DCs or macrophages to inhibit the development of Th1-type responses. It also inhibits Th2 cells and allergic responses. Tregs are an important source of IL-10 ...
Proinflammatory cytokines drive the early inflammation stage of wound progression. Fatty acids are known to play a role in cell membrane structure and anabolic (breaking down) events during skin tissue reconstruction by regulating the synthesis and activity of cytokines. Some research suggests omega-3s...
Although the mechanisms underlying the associations between GI and inflammation are not fully clear,some data showsthat rapid changes in blood sugar levels may increase free radicals and pro-inflammatory cytokines, leading to inflammation. In general, whole grains are associated with less inflammation th...
There is emerging information indicating that proinflammatory cytokines are important in the pathogenesis of CINP.191,192 Macrophages are accused of being involved in the neuroinflammatory process of the axons and neurons of dorsal root ganglion (DRG) in CINP. In response to che...
Once within the air spaces, these leukocytes are activated by proinflammatory cytokines to produce reactive species, which increase oxidant injury and lung scarring. 4. Secretion of growth factors from alveolar macrophages and alveolar epithelial cells. Release of such mediators stimulates fibroblast ...
Forastiero RR, Martinuzzo ME, de Larranaga GF. Circulating levels of tissue factor and proinflammatory cytokines in patients with primary antiphospholipid syndrome or leprosy related antiphospholipid antibodies. Lupus. 2005;14:129–36. PubMedCASGoogle Scholar ...
grade inflammation, with a transient increase in serum interleukin-6, induction of microglia, and greater expression of tumor necrosis factor-α positive cells in the frontoparietal cortex, consistent with the hypothesis that exposure to proinflammatory cytokines directly contributed to the EEG dys...
Interestingly, cancer-induced and chemotherapy-induced cachexia are characterized by distinct metabolic signatures. Thus, chemotherapy-induced cachexia promotes mi- tochondrial dysfunctions [95–97] independently from those caused by tumor-derived proinflammatory cytokines. Specific metabolite...