The efforts for the designing of the novel drug molecule is based on the concept known as molecular similarity; compounds with high molecular structural resemblance with pre-existing ligands, are more likely to have similar pharmacological activity profiles. This approach is considered an indirect ...
What are ancillary ligands? What is an ephemeris system? What is an antigen? What is an electrical unit? What is polysynthetic twinning? What is the epiphyseal line? What is anophthalmia? What does an accumulator do in a hydraulic system?
There are two main types of interstitials: - Interstitial atoms: These are usually smaller atoms that can fit into the spaces between the larger atoms in a crystal lattice. - Interstitial ions: Similar to interstitial atoms, these are ions that occupy interstitial spaces in ionic solids. 3. Ex...
Palladium Barium Sulfateis a commonly used catalyst with excellent catalytic performance and stability, widely applied in organic synthesis and hydrogenation reactions. This article will introduce the types of Palladium Barium Sulfate, compare it with other similar catalysts, and explore its application ...
There are two main cell death types: programmed cell death called apoptosis and unprogrammed cell death due to cell injury: necrosis. They differ in the signaling, biochemical, and morphological changes displayed by dying cells.
When transition metals are in solutions, they form complex ions with ligands. The electrostatic interactions between transition metal and the ligands... Learn more about this topic: Spectrochemical Series | Definition, Splitting & Ligands from
This approach identifies compounds similar to known active ligands based on their chemical structure or properties. The principle here is that compounds structurally similar to known active compounds are likely to exhibit similar biological activity in protein-ligand interactions. Two key methods used in...
Ligand binding is a process by which certain types of small triggering molecules join with a larger molecule to exert some kind of...
Their dynamic behavior is integral to their function, as proteins receive and respond to signals and changes within their native systems [Citation107–113]. Thus, introduction of changes in either binding partners or environment (temperature, solution conditions and binding of ligands) have a major ...
There are two types of quenching. What are they? What are their advantages, respectively? When the two types of quenching are applied, which one is first? Why? What is a back titration? What is its purpose and when is it used?