The effects of dietary bioantimutagens (compounds which have been shown to inhibit mutagenesis via interaction with DNA repair processes) on spontaneous and heterocyclic amine (HCA)-induced micronucleus (MN) frequencies were studied in metabolically competent human hepatoma (Hep-G2) cells, All the ...
Figure 2. Immunofluorescent analysis of 4% PFA fixed HepG2 cells using FIS1 and Alpha Tubulin antibodies. Green: FIS1 (10956-1-AP); Red: Alpha Tubulin (66031-1-Ig) Please remember to trust your dye! Using dyes is a simple and effective way to visualize organelles in your research, al...
Metabolic flux distribution during defatting of steatotic human hepatoma (HepG2) cells. Metabolites 2016;6(1):1. Duret C, Moreno D, Balasiddaiah A, Roux S, Briolotti P, Raulet E, et al. Cold preservation of human adult hepatocytes for liver cell therapy. Cell Transplant. 2015;24:2541...
- high grade: poorly differentiated cells that spread quickly staging for cancer refers to degree of spread - TNM - stage 1-4 Example of a endogenous antioxidant superoxide dismutase What are the main mechanism of cell injury 1. Ischemia 2. infection 3. Immune reactions 4. genetic factors 5....
The overall goal of this experiment is to determine if EGCG can serve as a potential anticancerous compound. In this experiment a starch assay was preformed to observed the cell migration of the HepG2 cells, when Get AccessRelated Gallbladder Carcinoma Gallbladder carcinoma (GBCs) is a ...
If large numbers of liver cells are infected with HAV, the person will develop symptoms. The viruses are secreted into the GI tract by the bile fluid made in the liver. The majority of people infected recover with no lasting damage to the liver. What Are the Signs and Symptoms of ...
Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cells. Toxicology 2011, 285, 18–24. [CrossRef] [PubMed] 28. Kourounakis, P.; Szabo, S.; Selye, H. Letter: Effect of various steroids and ACTH on methyprylon plasma levels and sleeping time in ...
Consistent with our observations in HepG2 cells, Tan increased nuclear Nrf2 accumulation and upregulated mRNA and protein levels of the Nrf2 target genes GCLC, NQO1 and HO-1 in C57BL/6J mice compared with mice treated with APAP alone. Tanshinone IIA protects against acetaminophen-induced hepatoto...
Hepatoma HepG2 cells (200,000 cells/well of 12-well plates) were pretreated with DMSO (vehicle, 0.1% v/v) or EPA and/or DHA (10, 25, or 50 [micro]M) for 3, 6, 16, or 24 H and then cultured for up to 24 H in the presence of a BA mixture (CDCA, CA, DCA, and LCA,...
Enlarged fat cells in obese adipose tissue diminish capacity to store fat and are resistant to the anti-lipolytic effect of insulin. Insulin resistance (IR)-associated S-nitrosylation of insulin-signaling proteins increases in obesity. In accordance with the inhibition of insulin-mediated anti-lipol...