H ThorntonAnnals of OncologyTobias JS, Baum M, Thornton H. Clinical trials in cancer: what makes for a successful study? Ann Oncol 2000; 11: 1371-1373.Tobias JS, Baum M, Thorton H. Clinicals trials in cancer: What makes for a successful study? Ann Oncol 2000; 11: 1371-3....
Clinical trials are the backbone of many new therapies, particularly cancer treatments, and most are conducted at universities or research hospitals. Most have specific inclusion/exclusion criteria that varies from trial to trial. For instance, one on an obesity drug might specify participants who hav...
Most randomised clinical trials of cancer treatment include a few hundred patients or less. Recent statistical papers advocate that sometimes thousands of patients should be entered. In this paper I show that for certain types of cancer trials the 'thous
It may also evaluate new ways of using known treatments, such as those used to treat cancer. Clinical trials determine whether new drugs, diagnostics, or treatments are safe and effective. Carefully conducted clinical trials are the fastest and safest way to find treatments that help people. ...
For decades, researchers at the University of Michigan Rogel Cancer Center have been searching for ways to fundamentally change the approach to treating laryngeal cancer and underlying assumptions to improve clinical care for patients. Laryngeal cancer c
In fifteen years of conducting clinical trials, monitoring or reviewing them for medical journals there has been little change in the general pattern, some are good, some are poor, a few are excellent and thankfully very few are unethical or dangerous. The advances in medicine seem to have co...
miRNAs are noncoding RNAs that negatively regulate target mRNA gene expression. Aberrant miRNA expression is associated with prostate cancer pathogenesis. ... I Casanova-Salas,J Rubio-Briones,A Calatrava,... - 《Journal of Urology》 被引量: 121发表: 2014年 Clinical Trials Have Gone Global: Is...
Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis Background Invasive ductal and lobular carcinomas (IDC and ILC) are the most common histological types of breast cancer. Clinical follow-up data and... Gulisa,Turashvili...
IMPORTANCE: Medications to reduce risk of breast cancer are effective for women at increased risk but also cause adverse effects. OBJECTIVE: To update the 2013 US Preventive Services Task Force systematic review on medications to reduce risk of primary (first diagnosis) invasive breast cancer in wom...
In the U.S., clinical trials are divided into five stages of research. Phase 0 -- also referred to as Early Phase I. This phase differs significantly from other phases of clinical trials as it is not a required part of testing for a new drug. However, the purpose of this phase is ...