Save difficult activities for when you are the most alert. Choose activities you are interested in doing. Keep mealtimes at the same time each day. Your healthcare providers can help you create a meal plan. Create a bathroom schedule. An example is going every 4 hours. Limit the amount ...
This means expanding the focus of mouse model research to include cognition, behavior, and measures closely corre- lated with these, such as synaptic and network function. Third, because clear sex differences exist in human AD epidemiology, specifically in progression to death, it is important to...
The “fatome” is the unique balance of fats we each consume in our diets that influences our health. Our optimal fatomes are unique to us and depend on our genomes, microbiomes, lifestyles, and nutritional perspectives.
Accept help from others.Caring for a sick loved one can be hard, both physically and mentally. Ask for help when you need it, whether that means letting a neighbor mow your lawn or hiring a health care aide to help out with home care. ...
Rea- sonably reliable genetic testing for predisposition to Alzheimer disease has been available commercially in the form of ApoE genotyping for many years now.6 Yet, the combination of the imperfect probabilistic nature of such information and the ut- ter lack of validated means to alter that ...
The gene that can most affect your risk of late-onset Alzheimer’s is apolipoprotein E (APOE). Everyone has some form (or variant) of APOE in their DNA. You’re more likely to develop the disease if you inherit the ɛ4 variant. On the other hand, having the relatively rare APOE ε...
The COVID-19 pandemic and subsequent measures implemented to prevent the spread of the disease, such as home confinement, are having a global impact on the mental health of the general population [1, 2]. Several studies conducted during this period indicated that the mental health burden of th...
Amino acids are essential to everything; they are the building blocks of life itself. If you are even missing one of these amino acids in your diet, your body will start to degenerate. Moreover, egg protein is highly available and digestible. This means you can absorb and more completely ...
Biologic sex and gonadal hormones matter in human aging and diseases of aging such as Alzheimer’s – and the importance of studying their influences relates directly to human health. The goal of this article is to review the literature to date on sex an
vector virus therapy [117] with a cell-type specific promoter or by using ligand-conjugated antisense oligonucleotides [118]. Importantly, for implementation of this strategy there likely needs to be better means of cell-type specific therapeutic modulation. Furthermore, modulation of pathways ...