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研究团队对每个家族的索引个体进行再分析,每个索引患者都接受了平均10倍深度的lrWGS检测。使用自体合子引导分析lrWGS数据,在34个家族中的13个(38%)中鉴定出候选变异。 lrWGS揭示WES无法检测到的分子诊断 1.TYMS作为致死性新生儿乳酸酸中毒的新候选基因 14DG1582是来自同一家庭的三名新生儿之一,他们在新生儿期死亡且经...
不对称双核基因组的减数分裂活性导致新染色体的形成,一些子细胞的非整倍性,以及大多数其他子细胞的不可存活。 参考文献: Deng Y, Guo L, Lin L, et al. Meiosis in an asymmetric dikaryotic genome ofTremella fuciformisTr01 facilitates new chromosome formation[J]. Genome Biology, 2023, 24(1): 280....
研究团队对每个家族的索引个体进行再分析,每个索引患者都接受了平均10倍深度的lrWGS检测。使用自体合子引导分析lrWGS数据,在34个家族中的13个(38%)中鉴定出候选变异。 lrWGS揭示WES无法检测到的分子诊断 1.TYMS作为致死性新生儿乳酸酸中毒的新候选基因 14DG1582是来自同一家庭的三名新生儿之一,他们在新生儿期死亡且经...
Axford R, Short S, and Shchupak P, et al.. Wideband Global SATCOM (WGS) earth terminal interoperability demonstrations [C]. Proc. Of IEEE MILCOM 2008, San Diego, CA, Nov. 16-19, 2008: 1-6.Axford R,Short S,Shchupak P,et al.Wideband Global SATCOM(WGS)earth terminal interoperability...
表1WGS反应中可能基元反应步骤的活化能数值单位:kJ·mol1)基元正反应(Ef)逆反应(Et)反应Cu(1Cu(1Pd(1Au(1Cu(1Cu(1Pd(1Au(110)11)11)11)10)11)11)11)①000058584267②9610910815024800③5867637196889267④806392742129825⑤0000505014242⑥45461003796117142203⑦212117170000注:表中X(111)表示不同金属的同一...