To reach these conclusions, the group used a gene-altered mouse model, feeding the mice either a normal diet or a Western diet for 12 weeks. The mice were also given the antibiotic doxycycline to activate the peptide NaKtide in the fat cells. The mice eating the Western diet increased thei...
Western diet for 7 weeks in apolipoprotein-E-deficient mice induces non-alcoholic steatohepatitis with significant liver fibrosis and portal hypertensionRobert SchierwagenLara MaybuechenChristian P. StrassburgChristian TrautweinJogchum PlatDieter Luetjohann...
Contact one of ournutrition scientists for assistance in finding the formula for you specific study needs. A Word of Caution Don’t be misled by diet manufacturers who claim to offer the same OpenSource diet formulas as Research Diets, Inc. Though it is true that all our formulas are open,...
it’s unknown whether factors such as diet and obesity play a role in who develops these symptoms. Now, researchers reporting inACS Chemical Neurosciencefound that mice fed a moderate-fat, high-sugar chow (simulating a Western diet) showed a faster decline...
2. A regulated selection of foods, as for medical reasons or cosmetic weight loss. 3. Something used, enjoyed, or provided regularly: subsisted on a diet of detective novels during his vacation. adj. 1. Of or relating to a food regimen designed to promote weight loss in a person or an...
Further tests by the researchers indicated that the Western diet triggered transcriptional changes in the animals’ bone marrow progenitor cells that persisted, even after the mice were put back on their regular chow. Despite this dietary switchback the genetic re...
www.nature.com/scientificreports OPEN LXR agonist modifies neuronal lipid homeostasis and decreases PGD2 in the dorsal root ganglia in western diet‑fed mice Nadia Elshareif, Chaitanya K. Gavini & Virginie Mansuy‑Aubert* The prevalence of peripheral neuropathy is high in ...
aAn outline depicting induction of NASH with a CL-HFS. Six-week-old WT C57BL/6 J mice were fed a CL-HFS or normal diet (ND) for 12 weeks. At week 18, each mouse was euthanized for the following studies.bRepresentative macroscopic images of livers in CL-HFS- and ND-fed mice.cRe...
High doses of bisphenol AF (BPAF), a widely used chemical in many products, has been reported to exert adverse effects on lipid or glucose metabolism, but whether low-dose exposure, especially in combination with a high-sugar, high-fat diet (Western diet, WD), has unacceptable effects remai...
5d,g), however, Abca1 was the only gene affected by 2HP-β-CD, as shown by the elevated mRNA levels in CD-fed mice. Figure 5 The Western diet promotes changes in the renal expression of genes involved in lipid metabolism. Determining the effect of the WD and 2HP-β-CD on the ...