加权基因共表达网络分析(Weighted Gene Co-expression Network Analysis,简称 WGCNA)是一种用于分析基因表达数据中基因之间相互关系的方法。 它通过构建基因表达的加权网络,利用基因之间的共表达模式来识别与特定表型(如疾病状态、性别、环境条件等)相关的基因模块。 WGCNA 通过计算基因对之间的相关性,构建加权基因共表达网...
GENE ontologyGLOMERULAR filtration rateBackground/Aims: Podocyte damage is associated with proteinuria, glomerulosclerosis and decline of renal function. This study aimed to screen critical genes associated with podocyte injury in chronic kidney disease (CKD) by weighted gene correlation network a...
Weighted Gene Co-expression Network Analysis (WGCNA) Part I, 视频播放量 0、弹幕量 0、点赞数 0、投硬币枚数 0、收藏人数 0、转发人数 0, 视频作者 sc-RNA-seq, 作者简介 scRNA-seq data analysis,相关视频:
Weighted Gene Co-expression Network Analysis (WGCNA) Part III, 视频播放量 0、弹幕量 0、点赞数 0、投硬币枚数 0、收藏人数 0、转发人数 0, 视频作者 sc-RNA-seq, 作者简介 scRNA-seq data analysis,相关视频:
(2)intramodular connectivity: 找出一个模块内的hub gene,来代表这个模块,通常这hub gene都是和E高度相关的。 计算模块的membership: 计算任意一个基因和模块(如蓝色模块)的相关性(无论这个基因是否在这个模块里),如果相关性为0,那这个基因就不在这个模块里,反之则在模块里。(E我们在上文中已经提过),对那些在...
The weighted gene co-expression network analysis (WGCNA) method, assuming that all kinds of proteins in the organism obey the basic assumption of scale-free network topology, is used to search for proteins or gene modules (A, B) that are co expressed based on the correlation algorithm, and ...
WGCNA: an R package for weighted correlation network analysis - PubMedpubmed.ncbi.nlm.nih.gov/19114008/ 如果对文中的概念不了解可进行翻译,查资料建议使用维基百科,后续如果有闲暇时间,或者需要对该篇内容的观点进行必要的修改,会对本篇分享进行二次加工进行更好的呈现,另外,对于基础概念有疑问请看一下...
The hub gene analysis showed several genes coding for ECM components as the most interconnected nodes in the gene network (e.g. COL4A1 , COL4A2 , LAMA2 , LAMA4 , FBLN5 and FBN1 ). In this regard, this study suggests that alterations in ECM composition could somehow activate the ...
11 samples in GSE41571 were used to identify the differentially expressed genes (DEGs) and to construct the weighted gene correlation network analysis (WGCNA) by R software. The gene oncology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment tool in DAVID website, and the ...
基因表达分析geneGene 系统标签: weightedgenenetworkexpressionanalysis基因 1 Weighted Gene Co-expression Network Analysis (WGCNA) R Tutorial, Part A Brain Cancer Network Construction Steve Horvath Correspondence: shorvath@mednet.ucla.edu, http://.ph.ucla.edu/biostat/people/horvath.htm This is part A...