Reports on the successful effort of the Mayo Clinic's division of communication in Rochester, Minnesota to ban a weight loss drug because users are developing valvular heart disease. Presentation of facts; Challenge of communicating study results without a formal scientific publication; Use of the ...
Drugs that promise to help people lose weight have had a checkered past, such as the infamous fen-phen that was pulled from the market in 1997 after reports of heart valve damage. But now, drug company pipelines are filling up with new molecules that aim to help people safely shed ex...
Safety issues with discontinued weight loss drugs Fenfluramine (Pondimin), used in the combination drug fen-phen (fenfluramine and phentermine) was associated with dangerous heart valve side effects and is no longer available on the U.S. market due to this side effect. Fenfluramine inhibits ...
If phentermine sounds familiar, it may be because it was one-half of fen-phen, the cult-status pill cocktail deemed the holy grail of weight loss in the ‘90s for its ability to kill appetite and dissolve the pounds away. Fenfluramine-phentermine ultimately ended up causing serious heart an...
Osborn invokes the weight-loss industry’s botched embrace of its previous “miracle drug,”fen-phen—which was effectively withdrawn from sale in 1997 after a year on the market for being linked to sometimes-fatal heart problems—and raises concern...
Eating healthy is great, too, but even with sustained changes to your diet, it’s notoriously difficult to maintain long-term weight loss. And most medical treatments now marketed for weight loss only provide a modest boost, if any at all, while past treatments like Fen Phen and 2,4-...
Even so, Novo was wary of using diabetes drugs explicitly for weight loss. The strategy was debated within the company. Knudsen says execs were haunted by rivals’ past failed attempts to capture the diet-drug market. The drugs fen-phen and Acomplia were both found, in the 1990s and 2000s...
Older weight-loss drug prescriptions rise Rates of weight-loss prescriptions among adults characterized as overweight have more than doubled since 2017, according to data fromEpic Researchbased on analysis of millions of electronic health records. Just from2022 to 2023, the data shows, rates jumped...
rejects the idea of obesity as a disease. Some of the same medical framing being used now for Ozempic and Wegovy were also in play during waves of earlier weight loss pills, Osborn said, including Fen-Phen, a nickname for an appetite suppression drug that was eventually pulled from the m...
If weight is lost in the initial 6 months of therapy or is maintained after the initial weight loss phase, this should be considered a success and the drug may be continued. The following medications have been approved by the FDA for weight reduction: Benzphetamine (Didrex), Diethylpropion (...