such as TNK t-PA (TNKase™, tenecteplase), hereinafter referred to as “tenecteplase,” is preferably administered as a single intravenous (IV) bolus, in combination with a low molecule weight heparin, such as LOVENOX® (enoxaparin sodium injection), hereinafter referred to as “enoxaparin.”...
Thelow molecular weight heparins(LMWH) are smaller than UH but maintain a critical peptide sequence that inhibits FXa, and to a lesser degree factor IIa. These drugs have no effect on theaPTTor PT, given the reduced inhibition of IIa.Dalteparin(Fragmin) andenoxaparin(Lovenox) have b...
An additional round of external validation [21] was performed to ensure the predictivity of the model using samples obtained from commercially available Enoxaparin Sodium; Lovenox™, Sanofi-Aventis, Bridgewater, NJ; Enoxaparin Sodium Injection, Sandoz, Princeton, NJ; and Enoxaparin Sodium Injection, ...