However, particles can also have positive health consequences when used for medical purposes such as drug delivery. Over the past decades, an enormous amount of knowledge has been amassed that describes the many different properties of particles and fibres that shape the responses they can evoke in...
would change. I thought that having a president like Barack Obama would shift something in America. Perhaps it did for some. But it was astonishing how the fearful gaze of White America transformed even Obama into another black male threat who was lynched online or labeled “Primate in Chief...
If we have two copies of a particular gene type, that’s calledhomozygous. If we have one copy of one type, and a different copy of another type, that’s calledheterozygous. Figure 5.1: Homozygous and heterozygous inheritance Interestingly, many traits that are supposedly one-gene, ormonogenic...
The majority of human and primate Vγ9/Vδ2 T cells responds rapidly to small phosphorylated molecules in vitro, often referred to as ‘phosphoantigens’ [3]. By far the most potent of these compounds is the microbial metabolite (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMB-PP...
aspirations as a species to all of our individual and collective actions. And this, in turn, demands rich, transparent public discourse and massive personal responsibility to leverage the many examples of positive deviance (Parkin2010) that are proliferating on the periphery, albeit mostly invisibly....
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Answer to: If all people have the same number of melanocytes in their skin, how do we explain the differences in color among the various races? By...
In a non-human primate model of infection, protective efficacy of the vaccine was tested in male 2–4 year-old rhesus macaques. The animals were immunized twice with 30 or 100 μg of BNT162b2, 21 days apart. Antibody concentrations were assessed by Luminex microsphere assay 7 days after th...
tuberculosis infection, or the rapidly progressive infections seen in SCID mice, as well as the increased mycobacterial growth in mice lacking the ability to produce or respond to IFNγ; in mice and in man there are similar examples of genetic mutations in the IFNγ-IL-12 axis resulting in ...
the human condition may impact predictive validity. Due to personal bias and familiarity, many of the examples cited will involve mouse models of neurological and neuromuscular diseases, but the principles should extend to many disorders and many model systems, and others will be mentioned throughout...