Warm autoimmune hemolytic anemia (AIHA) is defined as the destruction of circulating red blood cells (RBCs) in the setting of anti-RBC autoantibodies that optimally react at 37°C. The pathophysiology of disease involves phagocytosis of autoantibody-coated RBCs in the spleen and complement-mediated ...
The treatment of warm autoimmune hemolytic anemia (wAIHA) aims to suppress the autoimmune response, alleviate symptoms, and manage complications. Corticosteroids, such as prednisone, are often the first-line therapy, as they help suppress the immune system's abnormal activ...
To the Editor.—Shulman and colleagues1 describe a syndrome of autoimmune hemolytic anemia with both warm and cold autoantibodies. We, too, have followed
4Gehrs BC, Friedberg RC. Autoimmune haemolytic anemia. Am J Hematol. 2002; 69:258–271. doi: 10.1002/ajh.10062. 5Barros MM, Blajchman MA, Bordin JO. Warm autoimmune hemolytic anemia: recent progress in understanding the immunobiology and the treatment. ...
Diagnosis of the idiopathic warm antibody type of autoimmune hemolytic anemia requires evidence for hemolysis and autoimmunity against RBC's ie, a positive direct antihuman globulin test. In addition, underlying disease states and drug therapy must be excluded as causative factors. Therapeutic measures ...
Autoimmune hemolytic anemia with both cold and warm auto- antibodies. JAMA 1985; 253: 1746-8.Shulman IA, Branch DR, Nelson JM, et al. Autoimmune hemolytic anemia with both cold and warm autoantibodies. JAMA 1985;253: 1746-1748... IA Shulman,JM Nelson,DR Branch - 《Jama the Journal of ...
Warm Autoimmune Hemolytic Anemia (WAIHA) Pipeline Insight, 2020, report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in Warm Autoimmune Hemolytic Anemia pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers...
Abstract Introduction Research on mixed warm and cold autoantibodies in autoimmune hemolytic anemia (AIHA) targeting erythrocytes [red blood cells (RBCs)] and platelets is scarcely reported. Case presentation In this study, we present the case of a 5-year-old boy with positive direct [anti-IgG ...
Immune Hemolytic Anemias (2nd ed.), Churchill Livingstone, Philadelphia, PA, USA (2004) Google Scholar [6] W Barcellini, A Zaninoni, JA Giannotta, B. Fattizzo New Insights in Autoimmune Hemolytic Anemia: From Pathogenesis to Therapy Stage 1 J Clin Med, 9 (12) (2020), p. 3859, 10.339...
Post-Babesiosis Warm Autoimmune Hemolytic Anemia Background Babesiosis, a tickborne zoonotic disease caused by intraerythrocytic protozoa of the genus babesia, is characterized by nonimmune hemolytic anemia that resolves with antimicrobial treatment and clearance of parasitemia. The de......