et al. An integrative method for scoring candidate genes from association studies: application to warfarin dosing. BMC Bioinformatics 11 (Suppl 9), S9 (2010). https://doi.org/10.1186/1471-2105-11-S9-S9 Download citation Published28 October 2010 DOIhttps://doi.org/10.1186/1471-2105-11-S9-...
There is potential to improve the quality of anticoagulation control by simple algorithm-based warfarin dosing.doi:10.1161/circoutcomes.4.suppl_2.AP131Van, Spall HR., NieuwlaatL., WallentinS., YusufM.D., EzekowitzS., YangC., Kabali
Interestingly, a proposal has been made for a multicenter trial in Europe that will test pharmacogenetics-guided initiation with the use of genotype-based loading doses to examine the clinical utility of such dosing methods. The present study supports the use of a genotype-guided loading dose ...
Rapid INR testing at the ED or PCC dosing independent from the INR may avoid this delay in emergent situations [31,38,39]. Lastly, administration time may vary between 15 to 30 minutes depending of the volume given, which depends on the weight, the INR, and the maximum infusion time ...
In daily clinical practice, NOACs offer more benefit than warfarin due to: (1) rapid onset of action; (2) fixed dosing; (3) few drug to drug interactions; (4) few drug to food interactions; (5) no routine laboratory monitoring; and (6) short blood-thinning effect. However, NOACs al...