B. D. Horne et al., "Warfarin dosing algorithm refinements after 7-9 days of therapy based on pharmacogenetic, pharma- cokinetic, clinical, and laboratory data," Journal of the Ameri- can College of Cardiology, vol. 55, Article ID A130.E1218, 2010....
Proposal of pharmacogenetics- based warfarin dosing algorithm in Korean patients. J Hum Genet 2011;56(4):290-5.CHOI JR,KIM JO,KANG DR,et al.Proposal of pharmacoge-netics-based warfarin dosing algorithm in Korean patients.JHum Gene. 2011...
华法林还可干扰某些易栓症检测。 * There were no significant between-group differences for any characteristic. IQR denotes interquartile range. † This variable was used in the algorithms for dose initiation and dose revisi...
The objective of our present study was to develop a warfarin dosing algorithm for the Omani patients, as performances of warfarin dosing algorithms vary across populations with impact on the daily maintenance dose. We studied the functional polymorphisms of CYP2C9, CYP4F2 and VKORC1 genes to ev...
Implementing algorithm-guided warfarin dosing in an ethnically diverse patient population using electronic health records and preemptive CYP2C9 and VKORC1 genetic testing. Clin Pharmacol Ther. 2016;100(5):427–30. https://doi.org/10.1002/cpt.425. Article CAS PubMed Google Scholar Lee SY, ...
Patient: Version 4.0 Build : May 2, 2024 Welcome toWarfarinDosing.org, a free Web site to help doctors and other clinicians begin warfarin therapy by estimating the therapeutic dose in patients new to warfarin. This site is supported by the Barnes-Jewish Hospital at Washington University Medical...
Cini M, Legnani C, Cosmi B, Guazzaloca G, Valdre L, Frascaro M et al (2012) A new warfarin dosing algorithm including VKORC1 3730 G > A polymorphism: comparison with results obtained by other published algorithms. Eur J Clin Pharmacol 68:1167–1174 Article CAS PubMed Google Schol...
response (e.g., age; gender; weight; concomitant medications such as amiodarone, statins, and trimethoprim/sulfamethoxazole; tobacco use; and genotypes for CYP2C9, VKORC1, CYP4F2, and GGCX, if available). The output of the algorithm is an estimated initial and maintenance dose of warfarin....
Integration of genetic, clinical, and INR data to refine warfarin dosing. Clin Pharmacol & Ther. 2010;87:572–8. Article CAS Google Scholar Yan H, Yin JY, Zhang W, Li X. Possible strategies to make warfarin dosing algorithm prediction more accurately in patients with extreme dose. Clin ...
The researchers devised an algorithm that accounts for variants in these genes, initial INR and other clinical factors. They utilised data from two pharmacogenetic trials, which involved a total of 92 patients and assessed warfarin therapy after orthopedic surgery. Of note, the The...