Vimirogant (VTP-43742) hydrochloride 是一种选择性、具有口服活性的的 RORγt 抑制剂 (Ki=3.5 nM; IC50=17 nM)。Vimirogant hydrochloride 与 RORα 和 RORβ 比,高出 >1000 倍的选择性。Vimirogant hydrochloride 抑制小鼠脾细胞的 Th17 分化和 IL-17A 分泌 (IC50=57 nM),而不会影响 Th1,Th2 或 ...
98%+25mg¥0.00100 98%+50mg¥0.00100 98%+100mg¥0.00100 Online ConsultationShopping Cart Product safety Specification HF07977 Vimirogant hydrochloride/VTP-43742 Product Details Analogs can be customized for you. Chinese name:Vimirogant hydrochloride/VTP-43742 ...
英文名称:Vimirogant hydrochloride/VTP-43742 英文同义词:Vimirogant hydrochloride/VTP-43742;5H-Pyrrolo[3,4-b]pyridine-3-carboxamide, N-[[5-(ethylsulfonyl)-2-pyridinyl]methyl]-6,7-dihydro-7-(1-methylethyl)-6-[[trans-4-(trifluoromethyl)cyclohexyl]methyl]-, hydrochloride (1:), (7S)- ...
VTP-43742 (VTP43742) is a highly potent, selective, oral RORγt inverse agonist for the treatment of autoimmune disorders, including multiple sclerosis and psoriasis..Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet Cas No.: 1802706-04-2 Chemical Name: (S)-N-((5-(...