Vonoprazan Fumarate,又称富马酸沃诺拉赞,是可口服的抗胃酸药物,是一种钾竞争性酸阻断剂,可以可逆抑制胃中H + /K + -ATPase,抑制胃酸分泌,临床上用于糜烂性食管炎、胃溃疡、十二指肠溃疡的治疗。 产品信息 英文别名(English Synonym) Vonoprazan Fumarate, TAK-438, TAK438 ...
solubilityDMSO: 50 mg/mL (108.35 mM) formSolid colorWhite to Off-White InChIKeyROGSHYHKHPCCJW-WLHGVMLRSA-N SMILESC(/C(=O)O)=C\C(=O)O.S(C1=CN=CC=C1)(N1C=C(CNC)C=C1C1C=CC=CC=1F)(=O)=O FDA UNII4QW3X4AMLB Vonoprazan FuMarate Price ...
中文别名 Vonoprazan Fumarate;(881681-01-2) 英文别名 881681-01-2;Vonoprazan Fumarate CAS号 881681-01-2 SMILES CNCc1cc(n(c1)S(=O)(=O)c2cccnc2)c3ccccc3F.C(=C/C(=O)O)\C(=O)O Inchi InChI=1S/C17H16FN3O2S.C4H4O4/c1-19-10-13-9-17(15-6-2-3-7-16(15)18)21(12-13)24(22,...
Vonoprazan fumarate Product NameVonoprazan fumarate CAS1260141-27-2 CBNumberCB32628441 MFC21H20FN3O6S MW461.4634032 EINECS250-635-4 MDL NumberMFCD18633280 MOL File1260141-27-2.mol Chemical Properties storage temp.Store at -20°C solubilityinsoluble in H2O; insoluble in EtOH; ≥18.9 mg/mL in ...
Product name:Vonoprazan Fumarate Purity:98% min CAS NO:1260141-27-2 Solubility:DMSO : 50 mg/mL (108.35 mM) Molecular Formula:C21H20FN3O6S Package:Package according to customer requirements. Molecular Weight:461.463 Storage:Store at -20℃Quality...
(ASP) is prescribed to millions of people around the world as a secondary preventative strategy for the majority of significant cardiovascular events; however, it carries a substantial risk of gastric ulcer and bleeding. Cabpirin® tablets, which include low-dose ASP and vonoprazan fumarate (VON...
COA of Vonoprazan Fumarate Test items Specifications Result Appearance White or almost white crystalline powder White crystalline powder Solubility Soluble in DMSO, slightly soluble in methanol and water, very slightly soluble in ethanol Complied
Vonoprazanfumarate (Takecab®), discovered and developed by Takeda and Otsuka, was approved by the PMDA of Japan in December 2014, and is indicated for the treatment of gastric ulcer, duodenal ulcer and reflux esophagitis.271Vonoprazan fumarate has a novel mechanism of action called potassium-comp...
Compared with existing Vonoprazan salts, the salt formed by Vonoprazan and the complex of the organic acid and bismuth of the present invention has a number of satisfactory advantages, such as good solubility and stability, increased bioavailability, and synergistically increased efficacy. 展开 ...
Vanoprazan fumarate is a new oral gastric acidity drug developed by Takeda Pharmaceutical and Otsuka Pharmaceuticals. It is used to treat duodenal ulcers, gastric ulcers, reflux esophagitis, gastric ulcers or recurrent duodenal ulcers caused by low dosages of Aspirin, and Helicobacter pylori. It can...