OrganismTest TypeRouteReported Dose (Normalized Dose)EffectSource dog LD50 oral > 2gm/kg (2000mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 25, Pg. 815, 1994. mouse LD50 intravenous 7820mg/kg (7820mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 25, Pg. 815,...
Voglibose does not affect the pharmacokinetics of hydrochlorothiazidePublic HealthHealthy VolunteerOral DoseClinical PharmacologyPharmacokinetic ProfileReactions Weekly -doi:10.2165/00128415-199807110-00011NoneSpringer International PublishingReactions Weekly
Voglibose. React. Wkly. 728, 12 (1998). https://doi.org/10.2165/00128415-199807280-00044 Download citation Published20 February 2013 Issue DateNovember 1998 DOIhttps://doi.org/10.2165/00128415-199807280-00044 Keywords Type Diabetes Mellitus Ileus Cerebral Infarction Initial Dose Publish Case Report ...
Extent of absorptionPoorly absorbed (<2% as unchanged drug), bioavailability is low25mg completely absorbed; 100mg 50%–70% absorptionPoorly absorbed (<6%); absorption is dose dependent DistributionExtracellular fluidExtracellular fluidLumen of gastrointestinal tract ...
[16] Seino Y,Fujita T(Hiroi S) et al Ef,cacy and safety of alogliptin in Japanese patients with type 2 diabetes mellitus: a randomized,double-blind,dose-ranging comparison with placebo,followed by a long-term extension study[J] Curr Med Res Opin(2011)27(9): 1781-1792 [17]尹建梅,王霁...
However, the same dose of metformin was significantly less effective than Voglibose ® at the doses of 0.5 mg/kg and 1.0 mg/kg. Conclusion: The response to Voglibose ® (1 mg/kg) on the postprandial hyperglycemia is better than with metformin. However, when Voglibose and metformin were ...
Katsuno T, Wantanabe N, Nagai E, et al. Comparison of efficacy of concomitant administration of mitiglinide with voglibose and double dose of mitiglinide in patients with type 2 diabetes mellitus. J Diabetes Investig. 2011;2(3):204-209....
In a dose-dependent manner, voglibose significantly reduced postprandial increases of blood glucose, insulin, and C peptide. At the lower loads (0.5 and 1 mg voglibose three times daily), these effecB. GökeClinical Research Unit for Gastrointestinal EndocrinologyH. Fuder...
Methods : Twelve healthy male subjects were included in this double-blind cross-over study and received a single 1.75-mg dose of glibenclamide on the 8th day of continuous administration of either placebo (reference) or voglibose 5 mg t.i.d. (test). Blood samples were taken to determine ...
Safety and tolerance were determined by monitoring clinical and laboratory parameters.%Results: The final dose of mitiglinide was 22.9 卤 8.9 (mean 卤 s.d.) mg (0.41 mg/kg) daily. Mitiglinide reduced fasting plasma glucose and GA levels after 4 weeks and HbA1c levels after 8 weeks. ...