However, considering that lipoproteins function as carriers of serum lipids such as cholesterol and triglycerides, we hypothesized that lipoproteins can associate with certain drugs and mediate their transport into tissues in lipid-associated form. Here, in vitro and in vivo studies with low density ...
Full size image Changes in lipid structural and functional categories in VLDL of MetS The relative abundance of lipid components was analyzed and compared between groups with lipid classes (Fig. 3A–C), structural categories (Fig. 3D–F), and functional categories (Fig. 3G–I). The comparison...
Full size table Fig. 1 Manhattan plot showing the |–log10(p)| -values (y-axis) of the Wilcoxon Mann Whitney U test, testing for metabolite differences in plasma between normal weight and obese pregnant women, stratified by lipoprotein species. Scattered line: uncorrected α-level at ±log10...
Only metabolites that are significantly different in at least one comparison are included. HDL, high density lipoprotein; LDL, low density lipoprotein; VLDL, very low density lipoprotein Full size image In the comparison between metabolites of the VLDL and HDL species, SM C42:2, PCae C38:5, ...
Check access to the full text by signing in through your organization. Access through your organization Section snippets Materials Tissue culture flasks, 175 cm2, and multiwell plates, 9.6 cm2, were from Nunc (Roskilde, Denmark). Na125I was from Amersham (Buckinghamshire, UK) and fetal cal...
6Translation- al Medical Center for Stem Cell Therapy, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China Lipid accumulation, which may be caused by the disturbance in very low density lipoprotein (VLDL) secretion in the liver, can lead to fatty liver disease....
In mammals, VLDLR comes in four potential variants, one as full length form, one lacking the third LA repeat, and possibly both of them missing exon 16, which codes for the O-linked sugar domain, all of them are expressed in the mammalian brain [35]. In the retina, only the variant ...