A transgenic mouse model, such as the aforementioned Tg26 mouse, can be used to test our saCas9 system on HIV proviral excision but does not recapitulate clinical HIV infection/latency in terms of HIV-1 proviral copies/loci, random integration, various infected cell types, and the high rate...
Such results led us to investigate the neuroprotective effects of WRPE in KA-induced temporal lobe epilepsy model by analyzing the neurobehavioral and morphological effectiveness in the mouse brain, in addition to antioxidative, anti-inflammatory, and neuroprotective potentials of WRPE in vitro and in...