In Vivo Acute and Chronic Toxicity of Pendimethalin on Haematological and Biochemical Indices of African Catfish, Clarias gariepinus (Burchell 1822)Owolabi, Olufemi D.Adeyemi-Ale, Olutomi A.Egyptian Academic Journal of Biological Sciences. B, Zoology...
The important role of cytokines prompted the administration of cytokines as anti-cancer immunotherapy. Interleukin-2 (IL-2), first described in 1976 as a T cell growth factor [143], plays a central role in immune regulation and T cell proliferation [130]. IL-2 was approved by the US Food...
PJ-249 Crucial Role of H_2O_2 as an Endogenous EDHF and Erythropoietin during Acute Coronary Occlusion in Canine Collateral Microvessels in Vivo(Coronary c... Yada,Toyotaka,Shimokawa,... - 《Circulation Journal Official Journal of the Japanese Circulation Society》 被引量: 0发表: 2008年 ...
There are multiple promising treatment strategies for central nervous system trauma and disease. However, to develop clinically potent and safe treatments, models of human-specific conditions are needed to complement in vitro and in vivo animal model-bas
The transcription factor p53 is a vital tumor suppressor. Upon activation by diverse stresses including oncogene activation, DNA damage, hypoxia and nutrient deprivation, p53 activates a panoply of target genes and orchestrates numerous downstream responses that suppress tumorigenesis. Although early studies...
3.2. Liver and Acute Phase Response Other studies were focused on ascertaining the role played by cytokines secreted by hepatic m-Mo populations in the pathogenic mechanisms of hepatitis that appeared in domestic pigs during acute forms of ASF. From day 3 pi, histopathological studies revealed the...
Temiloluwa O. Prioleau 3 and Xia Zhou 1 1 Department of Computer Science, Columbia University, New York, NY 10027, USA 2 Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA 3 Department of Computer Science, Dartmouth College, Hanover, NH...
(Fig.2). CRISPR-induced mutations are set after the time of sgRNA library delivery, whereas with transposon mutagenesis mutations continue to occur during a screen due to transposition. This ability to accumulate mutations throughout tumor evolution mimics human cancer progression and allows for the ...
The combination of the NRF2 inhibitor ML385 with RSL3 synergistically targets acute myeloid leukemia [33]. Besides, ROS production in mitochondria leads to disturbances in the electron transport chain and ultimately triggers apoptosis via the activation of caspase-3 [35, 36] and our data showed ...
Microplastics (MPs) have attracted global interest because they have been recognized as emerging pollutants that require urgent attention. MPs are plastic particles with a size between 1 micron and 5 mm (1 µm-5mm); those measuring less than 1 µm are known as nanoplastics (NPs). MP is...