Raloff, Janet
In essence, Pauling said that heart disease is a manifestation of chronic scurvy, and atherosclerotic plaque is a mechanism evolved to repair or patch blood vessels and arteries damaged by chronic vitamin C deficiency. Linus Pauling also said that atherosclerotic plaque formation can be prevented or ...
reduces their proinflammatory responses to classical M1-polarizing activation316Lymphocytic myocarditis coincides with increased plaque inflammation and plaque hemorrhage in coronary arteries, facilitating myocardial infarction317Serum osteoprotegerin level predictsdeclined numerous of circulating endothelial- derived and...
We did not find significant associations between genetically predicted vitamin D status (Odds ratio (OR)=0.99,=0.91) and deficiency (OR=1.00,=0.97) with the risk of carotid artery plaque. We additionally explored the potential causal effect of vitamin D status on coronary artery calcification (...
Upon sun exposure, circulating 25(OH)D levels were shown to be slightly lower in obese individuals as compared to lean individuals, which could be explained by the fast uptake of vitamin D by AT, which in turn reduces the supplies of vitamin D metabolites needed for target tissues [1]. ...
A high menaquinone intake reduces the incidence of coronary heart disease. Nutr. Metab. Cardiovasc. Dis. 2009, 19, 504–510. [Google Scholar] [CrossRef] van Ballegooijen, A.J.; Beulens, J.W. The role of Vitamin K status in cardiovascular health: Evidence from observational and clinical ...
The inhibition of BMP signaling reduces vascular calcification [28]. Runx2 is a major target protein of the BMP pathway, which is a regulator of osteogenesis and is crucial for regulating the expression of bone specific genes. However, BMP2 signaling stimulates p300- mediated Runx2 acetylation, ...
[146], the vitamin K1 to slow VC in HD subjects study (VitaVasK) [147], the bicuspid aortic valve stenosis and the effect of vitamin K2 on calcification trial (BASIK2) [148], and the menaquinone-7 supplementation to reduce vascular calcification in patients with coronary artery disease ...