脾脏、胰腺等器官。分布 维生素Kvitamink的种类与作用 总结词 天然存在的维生素K1主要在绿色蔬菜中，是人体合成凝血酶原所必需的。详细描述 维生素K1有助于血液凝固，预防出血不止。它在肝脏合成凝血因子过程中起关键作用，缺乏维生素K1可能导致凝血障碍。此外，维生素K1还参与骨骼代谢，有助于维持骨骼健康。
An increasing number of aging-associated diseases are now recognized to be related to vitamin K2 insufficiency. Vitamin K1 is not commonly deficient: the vitamin K–dependent (VKD) clotting factors, which are carboxylated (activated) by K1 in the liver, have been found to be fully carbo...
Signs of a Vitamin K Overdose: Too much vitamin K1 may lower blood sugar levels. High doses may also increase the risk of blood clotting problems in people with severe liver disease, and interfere with certain blood-thinners, such as warfarin. Nausea, vomiting, and skin rash can also be s...
The vitamin K1 analog 2-chloro-3-phytyl-1,4-naphthoquinone (chloro-K) has proven to be very effective in warfarin-resistant rats, as it functions as a competitive inhibitor of the vitamin at the active site(s) in the vitamin K cycle. Other coumarins,19 2,3,5,6-tetrachloro-pyridinol, ...
a我坚信! 正在翻译,请等待...[translate] amore about this technique. 更多关于这个技术。[translate] aheavy rained 下雨的重[translate] aimma fight imma战斗[translate] a天然存在的维生素K有维生素K1和维生素K2 naturally occurring vitamin K vitamin vitamin K K 1 and 2;[translate]...
Figure 2. Structures of vitamin K active compounds. Phylloquinone (vitamin K1) synthesized in plants is the main dietary form of vitamin K. Menaquinone-9 is a prominent member of a series of menaquinones (vitamin K2) produced by intestinal bacteria, and menadione, vitamin K3, is a synthetic...
Disulfide-dependent protein folding is linked to operation of the vitamin K cycle in the endoplasmic reticulum: A protein disulfide isomerase-VKORC1 redox enzyme complex appears to be responsible for vitamin K1 2,3-epoxide reduction. J. Biol. Chem. 2007, 282, 2626–2635....
control 14.8 kg (6.5), p = 0.228) or development of gestational diabetes (n = 3 [5%] vs. n = 7 [5%], p = 1.000). Mean levels of vitamin K1 was lower after bariatric surgery compared with controls (0.29 [0.35] vs. 0.61 [0.65] ng/mL, p < 0.001). ...
According to these principles, it is likely that the response to vitamin K may be generalizable to all clinically used VKAs, but this would need to be verified experimentally. In conclusion, the results presented here confirm that the much higher antidotal potency of MK-7 than of vitamin K1 ...
Biochemically, VK has 3 known functions: the major is as cofactor in correct formation of special proteins including Osteocalcin, MGP (Matrix Gla Protein), Protein C and Protein S. The latter two (coagulation) roles can be performed by K1, K2 or K3, but Osteocalcin (bone) and MGP (cartil...