A definitive conclusion is still not possible Giving neonates vitamin K to prevent vitamin K deficiency bleeding (a more informative and accurate term than the venerable "haemorrhagic disease of the newborn") has been controversial almost since it began. In the 1950s synthetic menadione (Synkavit...
Vitamin K in neonates: How to administer, when and to whom Vitamin K-dependent factors are lower in neonates than in adults, and these anomalies are more prevalent in preterm neonates and in breast-fed infants. Vit... E Autret-Leca,AP Jonville-Béra - 《Pediatric Drugs》 被引量: 63发表...
Elimination half-life of vitamin K1 in neonates is longer than is generally assumed: implications for the prophylaxis of haemor- rhaghic disease of the newborn. Euro J Clin Pharmocol 1996;49(5):421-3.Elimination half-life of vitamin K 1 in neonates is longer than is generally assumed: ...
Neonatal vitamin K administration and childhood cancer in the north of England: retrospective case-control study. Objective: To explore the possible association between intramuscular vitamin K given to neonates and the subsequent development of childhood cancer. Design... L Parker,M Cole,AW Craft,.....
BASIC AND CLINICAL STUDIES OF CEFOTIAM IN NEONATES AND PREMATURE INFANTS patients, elevated GOT and GPT level in 1 patient, and the protein induced by vitamin K absence or antagonist (PIVKA II) became detectable in 1 ... S Iwata,Y Sato,Y Kusumoto,... - 《Japanese Journal of Antibiotics...
Both vitamins K3 and K4 may produce hyperbilirubinemia and kernicterus in neonates as well as hemolysis in neonates and glucose-6-phosphate–deficient patients. In fact, the only advantage of vitamins K3 and K4 over vitamin K1 is that whereas absorption of vitamin K1 requires the presence of bi...
Which of the following describes the rationale for administering vitamin K to every neonate A.Neonates don't receive the clotting factor in utero.B.The neonate lacks intestinal flora to make the vitamin.C.It boosts the minimal level of vitamin K found in the neonate.D.The drug prevents the ...
Vitamin K in neonates: Facts and myths. Blood Transfus. 2011, 9, 4–9. [Google Scholar] [PubMed] Dror, D.K.; Allen, L.H. Overview of Nutrients in Human Milk. Adv. Nutr. 2018, 9 (Suppl. 1), 278S–294S. Canfield, L.M.; Hopkinson, J.M.; Lima, A.F.; Martin, G.S.;...
Hemolysis, jaundice, and hyperbilirubinemia in neonates, particularly those that are premature, may be related to the dose of Vitamin K1 Injection. Therefore, the recommended dose should not be exceeded (See ADVERSE REACTIONS and DOSAGE AND ADMINISTRATION). Adverse Reactions/Side Effects Deaths have ...
because the commercial and clinically used formulation of vitamin K (Konakion MM) destabilizes at gastric pH resulting in low bioavailability of this vitamin in neonates with cholestasis.Mixed micelles composed of EPC, DSPE-PEG 2000 and glycocholic acid, with and without vitamin K, were prepared by...