The effect of warfarin and vitamin K-1 on the carboxylation and glycosylation of prothrombin in the rat in vivo was investigated. Neither warfarin nor vitamin K-1 has an effect on carboxylation. However, warfarin inhibited glycosylation 80–90% and this inhibition was readily reversed by the ...
We investigated the additional contribution of this polymorphism to the variance in warfarin dose. Methods: Sixty-five patients with stable anticoagulation were... Y Zhu,M Shennan,KK Reynolds,... - 《Clinical Chemistry》 被引量: 384发表: 2007年 The effect of dietary vitamin K on warfarin-induc...
Vitamin K/warfarin interaction: Decreased INR in an elderly patient taking a multivitamin: case reportBlood-coagulation-disordersDrug-interactionsElderlyVitamin-K, drug interactionsWarfarin, drug interactions
Vitamin K & warfarin (Coumadin) - Warfarin (Coumadin) patients should have a healthy, consistent intake of vitamin K in their diets.
Warfarin and other 4‐hydroxycoumarins are effective antithrombotic agents. They affect four blood coagulation proteins that act sequentially to produce thrombin. Coumarin therapy decreases the biological activity of these proteins, and therefore decreases the rate at which blood clots. As the mechanism ...
But, because of its effect on warfarin, some people try to avoid eating foods rich in vitamin K. The Benefits and Risks of Dietary Vitamin K: Vitamin K helps with blood clotting, bone density, and much more (NASDAQ: QDEL) has received CE Mark for its Sofia Quantitative Vitamin D FIA fo...
Vitamin K epoxide reductase (VKOR) catalyzes the reduction of vitamin K quinone and vitamin K 2,3-epoxide, a process essential to sustain gamma-carboxylation of vitamin K-dependent proteins. VKOR is also a therapeutic target of warfarin, a treatment for thrombotic disorders. However, the structu...
Vitamin K antagonists, such as warfarin, produce their effect on blood coagulation by interfering with the cyclic interconversion of vitamin K and vitamin K 2,3-epoxide. Vitamin K is an essential cofactor necessary for the posttranslational carboxylation of the glutamic acid residues on the N-termi...
aAlthough loneliness has always been a friend of mine but i will never give up on you! 虽然寂寞总是我的朋友,但我不会对您不抱希望![translate] along-standing vitamin K deficiency or the ingestion of warfarin and some wide-spectrum antibiotics 耐久维生素K缺乏或杀鼠灵和一些宽光谱抗生素的摄取[tr...
Effect of vitamin K administration on rate of warfarin reversal BACKGROUND Vitamin K is reported to begin reversing warfarin within 6 to 12 hours, but this may occur sooner. We sought to determine the rate of international normalized ratio (INR) reversal following vitamin K and relationships with...