For neonates at high risk of haemorrhage (premature, neonatal disease, birth asphyxia, difficult delivery, any illness which will delay feeding, known hepatic disease, maternal drugs inhibiting vitamin K activity), the first dose must be administered by the IM or slow intravenous route. Doses ...
Hemolysis, jaundice, and hyperbilirubinemia in neonates, particularly those that are premature, may be related to the dose of Vitamin K1 Injection. Therefore, the recommended dose should not be exceeded (See ADVERSE REACTIONS and DOSAGE AND ADMINISTRATION). Adverse Reactions/Side Effects Deaths have ...
Vitamin K deficiency is a common problem in the intensive care unit and a frequent cause of coagulopathy. Causes of vitamin K deficiency in the intensive care unit include prior deficiency, antibiotics, malabsorption, warfarin, and poor oral or enteral nutrition intake for prolonged periods of time...
Has been used to prevent vitamin E deficiency in premature neonates† [off-label].108Pharmacologic doses of vitamin E not recommended for prevention or treatment of retinopathy of prematurity† [off-label], bronchopulmonary dysplasia†, or intraventricular hemorrhage†.108...
Aim: The main objectives of this study were to determine the prevalence of vitamin D insufficiency in neonates with severe comorbidities and to evaluate whether high-dose vitamin D3 oral administration leads to normal plasmatic concentrations without side effects. Methods: The current study was a ...
D3had enhanced innate immune fitness [25]. Although there is accumulating evidence of the protective effects of vitamin D supplementation in neonates and in early life against asthma [26] it is still unclear what are the appropriate doses for optimal protection during pregnancy and early childhood...
concentration (74). Because of the multiple factors af- fecting a person's vitamin D status, providing supplementa- tion with a daily dose of 400 IU does not guarantee that a mother's measured 25D serum concentration will rise to a value sufficient for an exclusively breastfeeding infant. ...
Prolonged exposure to hyperoxia can lead to hyperoxic acute lung injury (HALI) in preterm neonates. Vitamin D (VitD) stimulates lung maturation and acts as an anti-inflammatory agent. Our objective was to determine if VitD provides a dose-dependent protective effect against HALI by reducing infla...
Since 1961 the American Academy of Pediatrics has recommended that all neonates receive a single intramuscular dose of 0.5-1 mg of vitamin K for the prevention of VKDB [11]. NICE guidelines of 2015 reiterated the recommendation to administer vitamin K at birth; in particular, they recommended ...
M.V.I. Adult is a combination product that contains the following vitamins: ascorbic acid, vitamin A, vitamin D, thiamine, riboflavin, pyridoxine, niacinamide, dexpanthenol, vitamin E, vitamin K, folic acid, biotin, and vitamin B12. M.V.I. Adult is supplied as a single dose or as a ph...