This prospective study compared PIVKA-II and PT-INR levels in infants who received two vitamin K (VK) prophylactic regimens.A single institution administered 119 healthy newborns 2mg of VK syrup. Infants were assigned to a 3-time regimen ( n =56) with VK at birth, five days (5D), and ...
When a doctor prescribes Warfarin, they are trying to balance it with how much vitamin K you eat (17) Regularly check your PT/INR levels Take the same amount of Warfarin at the same time each day Keep your intake of vitamin K consistent from day to day Eliminate alcohol if you can,...
Vitamin K & warfarin (Coumadin) - Warfarin (Coumadin) patients should have a healthy, consistent intake of vitamin K in their diets.
Vitamin K deficiency is a common problem in the intensive care unit and a frequent cause of coagulopathy. Causes of vitamin K deficiency in the intensive care unit include prior deficiency, antibiotics, malabsorption, warfarin, and poor oral or enteral nutrition intake for prolonged periods of time...
In addition to genetic factors mentioned above, dietary factors and a number of disease states affect the pharmacodynamic response to the VKA. Fluctuating intake of dietary vitamin K has been demonstrated to have an influence on maintenance of therapeutic international normalized ratio (INR) with long...
Prothrombin time (PT) is the leading test for monitoring oral anticoagulation therapy (OAT). We sought to determine INR taking into account only active coa... J Horsti,H Uppa,JA Vilpo - 《Open Medicinal Chemistry Journal》 被引量: 9发表: 2008年 A New Generation Prothrombin Time Method for...
Thus, the biological action of vitamin K on hemostasis, mediated by function of the VKORC1 enzyme, is entirely dependent on vitamin K nutritional status and, occasionally, on treatment with oral anticoagulant drugs. Very recently, evidence has been presented that a sec...
Warfarin is widely used, but its dominance is being challenged by novel non-vitamin-K antagonist oral anticoagulants such as dabigatran, rivaroxaban, apixaban, and edoxaban.201 Individual response to warfarin is highly variable and is monitored by INR (see Box 11.1).202 A 10% increase in time ...
were normal (PT 12.4 s, INR 0.94, aPTTs 28.5 s, aPTT-r 0.98, PLT 328,000/μl, fibrinogen 414 mg/dl) and hemoglobin values were increased (Hb 9.8 g/dl). The child was discharged with the indication to continue oral vitamin K supplementation with Konakion 10 mg twice weekly until ...
PT: prothrombin time INR: international normalised ratio PIVKA: protein induced by vitamin K absence ucOC: under-γ-carboxylated osteocalcin BMD: bone mineral density References American Academy of Pediatrics, Committee on Nutrition (1961) Vitamin K compounds and their water soluble analogues: ...