M. (1942). Is adminis- tration of vitamin K to the newborn of clinical value? J. Amer. med. Ass., 118, 697.Sanford HN, Shmigelsky L, Chapin JM. Is administration of vitamin K to the newborn of clinical value? JAMA 1942;118:697-702....
A prompt response (shortening of the prothrombin time in 2 to 4 hours) following administration of vitamin K1 is usually diagnostic of hemorrhagic disease of the newborn, and failure to respond indicates another diagnosis or coagulation disorder. Vitamin K1 Injection 1 mg should be given either ...
vitamin C functions as a cofactor in hydroxylation reactions. Vitamin D has hormonelike activity in calcium metabolism; vitamin A plays a critical role in night vision, growth, and maintaining normal differentiation of epithelial tissue; and vitamin K has a unique posttranscriptional role in the for...
Plasma levels of vitamin K (VK) and VK dependent proteins ( factor E, factor VH, factor X, protein C and osteocalcin)were determined before and after VK administration to 22 newborn infants. Vitamin K2syrup ( 2 mg/kg of body weight ) was orally administered to 9 healthy premature, 11 ...
We looked at existing recommendations and supporting evidence on the effectiveness of vitamin K given after birth in preventing the haemorrhagic disease of the newborn (HDN).#We conducted a literature search up to the 10th of December 2019 by using key terms and manual search in selected sources...
Discusses issues on vitamin K deficiency among newborn infant. Complications of the deficiency; Occurrence of hemorrhagic disease of the newborn; Results of a study on the association between childhood cancer and pethidine and vitamin K administration in Great Britain; Recommendations of the American ...
Objectives: To describe rates of newborn vitamin K prophylaxis uptake according to method of administration (intramuscular [IM], oral, refused) and identify predictors for the choice of oral administration and for refusal of vitamin K prophylaxis. Methods: A retrospective cohort study examined the re...
In newborn infants, the absence of intestinal bacteria, low levels of vitamin K in the mother’s milk, or the absence of body stores of vitamin K may result in bleeding, which can be prevented by the administration of vitamin K to the infant shortly after birth. (See table of the ...
Specifically, heparins require intravenous (unfractionated heparin; UFH) or subcutaneous (low molecular weight heparin; LMWH) administration and UFH requires frequent monitoring and adjusting of drug levels. Vitamin K antagonists also require frequent monitoring to maintain the anticoagulant capacity (as ...
4. L. Parker et al., "Neonatal vitamin K administration and childhood cancer in the north of England: retrospective case-control study," BMJ (England) 316, no. 7126 (Jan 1998): 189-93. 5. S.J. Passmore et al., "Case-control studies of relation between childhood cancer and neonatal ...