Their biological activity is expressed as vitamin E activity. This article describes the current need for vitamin E production, and compares different strategies to engineer the vitamin E content in photosynthetic bacteria and plants, with a focus on oilseed as target tissues. The current status of...
5-LO has been discussed as potential target of vitamin E before20,21. Thus, Goetzl reported in 1980 that the most abundant vitamin E form in mammalians, α-T (1a), modulates the lipoxygenation of AA in leukocytes20. Other forms of vitamin E were described to inhibit cellular LT formatio...
The end product of toxicant reacts with the endogenous target molecule like receptors, enzymes, DNA, protein, or lipid and seriously alters the biological micro environment, resulting structural and functional changes due to toxic damage. Heavy metals intoxication leads to increased lipid peroxidation ...
1α,25-dihydroxy-vitamin D3 (lα,25(OH)2D3; calcitriol) and estrogen (17β-estradiol) act, as other steroid hormones, through two different mechanisms. In addition to regulating expression of target genes via their specific nuclear receptors (VDR and ER, respectively), both hormones induce ...
and decreased between OSKM and OSKM + B12conditions in MEF 1 fromaandb. The top enriched GO biological processes (P < 0.005) are shown.Pvalues were determined by hypergeometric test; no multiple-comparisons adjustment was performed.e, H3K36me3 ChIP–seq and RNA-seq tracks from the...
1. The purpose of this review article is to re-evaluate and integrate many of the observations related to the physiological effects of vitamin D, using as ... AW Norman - 《Biological Reviews of the Cambridge Philosophical Society》 被引量: 24发表: 2010年 ...
Minimally invasive transcriptome profiling in salmon: Detection of biological response in rainbow trout caudal fin following exposure to environmental chem... An increasing number of anthropogenic chemicals have demonstrated potential for disruption of biological processes critical to normal growth and developme...
Ureases are multifunctional proteins that display biological activities independently of their enzymatic function, such as induction of exocytosis and inse... Defferrari, M. S.da Silva, R.Orchard, I.Carlini, C. R. - 《Toxicon An International Journal Devoted to the Exchange of Knowledge on the...
Vanzetti, 5, 20133 Milano, Italy; 2Division of Public Health, Department of Family & Preventive Medicine and Huntsman Cancer Institute, University of Utah School of Medicine, 375 Chipeta Way, Salt Lake City, UT 84108, USA; 3Department of Medical and Biological Sciences, University of Udine, ...
In target tissues, calcitriol binds to VDR, a member of the nuclear receptor family of ligand-activated transcription factors and which induces both genomic and non-genomic regulation of downstream targets involving diverse biological functions2,27,28. In the genomic pathway, calcitriol binds to cytos...