Introduction Up to 70% of pediatric patients have low vitamin D (VD) levels prior to hematopoietic stem cell transplantation (HSCT). In addition to the known adverse effects of VD deficiency on bone health, studies have found that patients with VD deficiency before and at day +100 have ...
Up to about a decade ago, there was tremendous uncertainty about vitamin D supplementation for the maintenance of adequate health levels. Large, randomized placebo-controlled trials with clinically important outcomes and/or surrogates had yet to be performed and only a few meta-analyses of randomized...
Supplementation with calcium and vitamin D3 can rarely unmask subclinical primary hyperparathyroidism. If hypercalcaemia is detected at this stage, participation will be discontinued with onward referral to clinical services. Table 1 Definitions of adverse reactions and events Full size table Strategies ...
Vitamin D Supplementation Guidelines for General Population and Groups at Risk of Vitamin D Deficiency in Poland-Recommendations of the Polish Society of Pediatric Endocrinology and Diabetes and the Expert Panel With Participation of National Specialist Co ...
A new clinical trial by researchers at Cincinnati's Shriners Hospital for Children compared the outcomes of vitamin D2 and D3 supplementation on pediatric burn patients. The results of that research was published today in the OnlineFirst version of theJournal of Parenteral and Enteral Nutrition(JPEN...
An increased risk of viral upper respiratory tract infections (URTI), asthma-related hospitalizations and use of anti-inflammatory medication have all been linked with low vitamin D. No study has determined whether wintertime vitamin D supplementation can reduce the risk of URTI and asthma ...
In pediatric and adult populations, several trials have failed to show a significant benefit of vitamin D supplementation on respiratory outcomes, including asthma or upper respiratory infections.14,27-29 In addition, in a study of extremely preterm infants, vitamin D did not affect duration of res...
Volume 76 | Number 2 | August 2014 Pediatric Research 181 Articles Ziegler et al. In conclusion, the four different vD supplementation doses led to significantly different plasma levels of 25(OH)D. At the start of the trial at 1 mo, the majority of infants had ...
Table 1 Pros and Cons of vitamin D supplementation in EoE Pros Cons Endogenous hormone Natural and easy to acquire in form of sunlight or pill Has benefit in other type 2 disorders and may potentially have a similar mechanism of action In combination with treatment (diet/drugs), it ...
Full size table Treatment Group After supplementation, there was a large and very significant increase in the level of CoQ10, and the levels of ATP, NADH, and NADPH all increased very significantly to normal levels. Figure 5 provides a comparison of the biomarkers that changed significantly from...