In addition the study included the evaluation of known risk factors and their correlation to the vitamin D status among girls aged 11 - 17 years in Rafsanjan during the winter of 2009.Methods: In a cross-sectional study, 250 healthy female students (age range, 11 - 17 years) were selected...
4. In this context, previous epidemiological investigations have proposed a seasonality in female reproductive capacity which might be explained partially by seasonal variation in serum levels of vitamin D5. Biological activities of vitamin D are applied through the vitamin D receptors (VDR) that have...
This procedure to estimate the power can be repeated for a range of possible values of n to construct a power function for the comparison. At first glance, this may appear to have a heavy computational load. Note however that these simulations may be easily parallelized using, for example, ...
Findings In this secondary analysis of a randomized clinical trial with 25 871 patients, supplementation with vitamin D3 reduced the incidence of advanced (metastatic or fatal) cancer in the overall cohort, with strongest risk reduction in individuals with normal weight and no reduction among indiv...
Only three subjects had a concentration within the normal range (10-55 ng/ml). Plasma 25-OH vitamin D concentrations were significantly lower in subjects living in apartments than in those living in villas or rural areas (P less than 0.02). When direct questioning was used to assess exposure...
The salient observation of the current work is that functional vitamin D3 receptors (VDRs) are expressed in a broad range of normal and malignant cells whose origin is related to the germline. In addition, it is known that the VDR is not only expressed by ovarian and testicular cancer cells...
The risk of gout did not significantly differ between the extreme categories of dietary vitamin C intake (multivariate RR <50 to >300 mg/d: 1.13; 95% CI, 0.69-1.83), but the range of intake was substantially smaller than for total or supplemental vitamin C intake. We conducted stratified ...
used to describe the range of the concentration of 25(OH)D reported for these two countries. Studies involving different cohorts (the Asturias study and the Pizarra study) in Spain estimated a slightly different concentration of 25(OH)D among the Spanish population. This led us to estimate a ...
Vitamin D deficiency is a candidate risk factor for osteoporosis, characterized by decreased bone mineral density (BMD). We performed this two-sample Mendelian randomization (MR) analysis to investigate the causal effect of vitamin D on BMD. We extracted 143 single-nucleotide polymorphisms from a re...
Vitamin D3 acted as a vital substance in human body, many diseases, such as type 2 diabetes11, cancer12, autoimmune diseases13,14, proteinuria15, hypertension16 would occur when vitamin D3 levels were below normal10. Previous studies have demonstrated that vitamin D3 might be a potential ...