Seasonal Affective Disorder (SAD)is a mood disorder characterized by depression that occurs during fall and winter months when sunlight levels are low. SAD typically coincides with a sudden drop in Vitamin D levels in the body. Several studies have suggested thatSAD could be due to changing Vitam...
The aim of the study was to examine possible variations in the levels of 25-hydroxy vitamin D [25-(OH)D] in sera from normal Biozzi and C57BL/6 mice and during the course of chronic relapsing experimental autoimmune encephalomyelitis (CR EAE).Serum concentrations of 25-(OH)D were measured...
Low vitamin D levels have been associated with cognitive decline; however, few randomized trials have been conducted. In a trial, we evaluated vitamin D3 supplementation on cognitive decline. We included participants aged 60+ years (mean[SD] = 70.9[5.8] years) free of cardiovascular disease...
Children with BMI > 95 percentile had significant higher prevalence of 25(OH)D deficiency (25(OH) D < 20 ng/mL) compared to their normal counterparts with BMI 5- 85 percentile (p = 0.036) (Fig. 3). The dis- tribution of 25(OH)D levels according to gender and...
supplemented individuals (HR 0.87, 95% CI 0.79–0.96;P = 0.005). As the final serum concentration of 25OHD in the VITAL trial (~110 nmol/l) and the ViDA trial (~125 nmol/l or 50 ng/ml) were in the high normal range it is unlikely that higher doses would be more ...
However, in animals and humans deficient in vitamin K, the pharmacological action of vitamin K is related to its normal physiological function, that is, to promote the hepatic biosynthesis of vitamin K dependent clotting factors. The action of the aqueous dispersion, when administered intravenously,...
Vitamins are a heterogeneous group of organic substances that are present in our natural foods, that are of very high biological potency and that are required in extremely small concentrations for growth and maintenance of normal cells and body function.
25-hydroxyvitamin D3 (25(OH)D3) is the inactive precursor of 1,25(OH)2D3and is considered the best parameter for evaluation of the vitamin D status of a subject. The normal range of serum 25(OH)D3concentrations is 25-170 nM [17]. The serum concentration of the active 1,25(OH)2D...
Vitamin D deficiency is a candidate risk factor for osteoporosis, characterized by decreased bone mineral density (BMD). We performed this two-sample Mendelian randomization (MR) analysis to investigate the causal effect of vitamin D on BMD. We extracted 143 single-nucleotide polymorphisms from a re...
No previous study has evaluated the associations of dairy products, lactose, calcium and vitamin D with the risk of ovarian cancer in African–American women, who are known to have high mortality from the disease, as well as to be at risk for calcium and vitamin D deficiency. Methods: We ...