The serum concentration of 25(OH)D that is felt to constitute adequacy is a subject of much debate and the recommended threshold used to define VDD is highly variable between guidelines and consensus statements (Table1), and this can limit the comparison of reported prevalence between studies. T...
All studies done with D2 will need to be repeated with D3; if the studies were negative, they need to be repeated to see if they are also negative with D3; if they were positive, they need to be repeated with D3 to see if the effect size is the same or not. Most milk now co...
intestine and bone1. Vitamin D also has direct and indirect effects on growth plates, bone and bone cells1. The extra-skeletal role of vitamin D has been suggested in various organs and ailments like skin (psoriasis,
Conclusion As 84% of vitamin D deficient children were asymptomatic, we conclude that "at risk" children should be proactively investigated. Early treatment of vitamin D insufficiency would prevent the subsequent necessity for more expensive treatment of deficiency. As a significant proportion received ...
Beyond cardiovascular diseases, vitamin D insufficiency could result in non-human great apes being more susceptible to bacterial or viral upper respiratory tract infections or pneumonia which are a common cause of morbidity in these species65,66,67. Our study shows that a considerable proportion of ...
(m)2]), fruit, vegetable and salt intakes, blood pressure, female life stage and selected health conditions. Participants were then randomly assigned to the NHS (n = 20,426), where health and medical information was collected, or the NNPAS (n = 12,153), where information ...
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet 2010; 376: 180–188. 42 Belvederi Murri M, Respino M, Masotti M, Innamorati M, Mondelli V, Pariante C et al. Vitamin D and psychosis: mini meta-analysis. Schizophr Res 2013; 150: 235–239....
In clinical studies, VitD3 insufficiency is thought to contribute to asthma27and supplementation of VitD3 resulted in a reduction of the number of exacerbations in asthmatic patients28. Generally, its mechanism of action involves both directing the immune system towards a tolerogenic response, and ...
Furthermore, prolonged vitamin D insufficiency has been associated with further health problems in adulthood, including cardiovascular disease, diabetes and autoimmune diseases [24,25], with implication for future costs to the UK’s National Health Service (NHS). There has been much discussion and ...
(31.8 ng/mL). There was no association between vitamin D serum concentration and dietary intake of vitamin D (p> 0.05), whereas there was a significant correlation with use of vitamin D supplements (r = 0.41;p< 0.001 in pregnant women and r = 0.35;p< 0.001 in postpartum women). This...