The amount of vitamin D you need to treat your deficiency depends on how deficient you are and your risk factors. Your doctor may start you on a higher dose of 6,000 IU of D3 a day. Once your level goes above 30 nanograms per milliliter, you will usually take a 1,000-2,000 IU...
For daily dosing in patients older than 64 years, 792 to 2,000 IU vitamin D per day decreases the risk of hip fracture by 30% and nonvertebral fracture by 14% compared with placebo (SOR: A, meta‐analysis RCTs). For monthly dosing in elderly ...
其突出的表现是小 儿的佝偻病(rickets)和成人的骨软化症(osteomalacia)并同存骨质疏松症 (osteoporosis),同时影响神经、肌肉、造血、免疫等组织器官的功能,严重 影响儿童的生长发育。 【流行病学】 佝偻病和骨质软化症都是由于膳食中缺乏维生素D或人体缺少阳光照射, 体内维生素D的合成减少,造成维生素D缺乏,从而形成骨...
Vitamin D testing and the use of vitamin D supplements have increased substantially in recent years. Currently, the role of vitamin D supplementation, and the optimal vitamin D dose and status, is a subject of debate, because large interventional studies have been unable to show a clear benefit...
Elderly:A study conducted to establish the vitamin D requirements in adults 64 years of age and older during the winter determined a recommended dose between 7.9 and 42.8 mcg daily to maintain a serum 25(OH)D level of 25 ng/mL; an evidence-based review recommends 800 to 1,000 units/day...
Osteoporosis(bone density scans show bone loss) Poor oral health Skin wounds that take a long time to heal. If the deficiency continues unresolved, then more noticeable symptoms may occur, such as bone fractures, rickets, orosteomalacia.
Having too little of these vitamin D metabolites in the body results in the failure to control calcium homeostasis, causing osteoporosis, osteomalacia and rickets. Rickets is a particularly devastating disease characterized by softened bones (leading to deformity) as well as muscle spasms and seizures...
Osteoporosis (thin and weakening bones in older adults) How Much Vitamin D Do You Need? A vitamin D deficiency is extremely common. Over one billion people worldwide, across all countries, ages, and ethnicities, have low vitamin D. (1) ...
This leads us to many studies done to show that vitamin D has no effect in the treatment of the same diseases stated above. It should be interesting to note that in these studies, they always talk about dose and not what the serum vitamin D is. One study suggested that “large doses”...
Vitamin D analogs and treatment of age-related osteoporosis Besides pharmacological intervention with bisphosphonates, RANKL inhibitor (antiresorptive compounds), and PTH peptides (anabolic drug, teriparatide), vitamin D analogs have also been studied for possible osteoporosis treatment. However, their thera...