Vitamin D deficiency is identified as a risk factor for gestational diabetes mellitus (GDM). Forkhead box class O1 (FoxO1) is closely related to GDM; however, the role of vitamin D deficiency and the underlying pathogenesis of GDM has not been elucidated. Serum vitamin D level was detected us...
Experimental factors Broncho-alveolar lavage fluid and lung homogenate obtained after in vivo exposure to cigarette smoke and/or vitamin D deficiency post-infection with NTHi Experimental features mRNA and protein expression of inflammatory cytokines and key markers of bacterial clearance pathways Data sour...
Li SR, Tan ZX, Chen YH, Hu B, Zhang C, Wang H, Zhao H and Xu DX: Vitamin D deficiency exacerbates bleomycin-induced pulmonary fibrosis partially through aggravating TGF-β/smad2/3-mediated epithelial-mesenchymal transition. Respir Res. 20(266)2019.PubMed/NCBIView Article:Google Scholar ...
Cells are constantly exposed to environmental stresses including the abundance or lack of key nutrients and may respond rapidly by decreasing cellular key protein contents, as well as proliferation rate to ensure their survival.1One of these nutrients is vitamin B12, whose deficiency produces neurodegen...
The persistence of biochemical VA deficiency may be due to impaired VA transport as transthyretin, a major VA transport protein, is reduced by inflammation (5). Retinoids are important for normal lung development and maturation (6,7). Hyperoxia induces lung injury, and may contribute to BPD (1...
Vitamin D deficiency was monitored by serum calcium analysis and normal serum calcium levels for mice are 2.00–2.75 mmol/L [29]. LPS was measured by Limulus quantitative azo color (LQAC) test. Assessment of disease activity Rachmilewitz DAI was assessed by an investigator blinded to the ...
Kumar A, Kumari S, Poojary D, et al. Estimation of serum micronutrient levels and the possible risk of oral cancer and premalignancy. Int J Innov Res Sci Eng Technol. 2014;3:8360–3. Google Scholar Siassi F, Ghadirian P. Riboflavin deficiency and esophageal cancer: a case control-househ...
and impaired GGCX activity has been associated with insufficientγ-carboxylation of prothrombin in cancers [37,38], while levels of GGCX mRNA have been shown either increased or heterogeneous among hepatocellular carcinomas [39]. Although prolonged subclinical vitamin K deficiency has been demonstrated ...
Vitamin D deficiency exacerbates atypical antipsychotic-induced metabolic side effects in rats: involvement of the INSIG/SREBP pathway. Eur. Neuropsychopharmacol. 25, 1239–1247 (2015). Article CAS Google Scholar Pittas, A. G., Lau, J., Hu, F. B. & Dawson-Hughes, B. The role of ...
Vitamin A deficiency increases susceptibility to skin infection. However, the mechanisms by which vitamin A regulates skin immunity remain unclear. Here, we show that resistin-like molecule α (RELMα), a small secreted cysteine-rich protein, is expressed by epidermal keratinocytes and sebocytes and...