Vitamin D and type 1 diabetes mellitus: state of the art. Trends Endocrinol Metab. 2005;16:261–6.Mathieu, C, Badenhoop, K (2005) Vitamin D and type 1 diabetes mellitus: state of the art. Trends Endocrinol Metab 16: pp. 261-266...
type 1 diabetes mellitusvitamin D levelIntroduction Type 1 diabetes mellitus (T1DM) is a lifelong metabolic disorder, which accounts for 10% of all cases of diabetes. Vitamin D deficiency is extensively studied in the pathogenesis of T1DM. Vitamin D regulates both innate and adaptive immunity, ...
Recent evidence suggests a role for vitamin D in pathogenesis and prevention of diabetes mellitus. Active vitamin D, 1α,25(OH) 2D 3, prevents type 1 diabetes in animal models, modifies T-cell differentiation, modulates dendritic cell action and induces cytokine secretion, shifting the balance to...
但要注意一点:维生素D是脂溶性维生素,容易在体内堆积,长期摄入大量维生素D补充剂,可能会发生过量或中毒。因此,要在医生或营养师指导下服用。 如果你觉得这篇文章有帮助,帮我们点点“赞”和“在看”吧! 参考文献: [1]Pittas A G, Kawahara T, Jorde R, et al. Vitamin D and risk for type 2 diabetes in...
Vitamin D Levels in Children With Type 1 Diabetes MellitusInsulin oedema is a rare condition which should be considered in children who present with oedema following insulin therapy in the absence of any other cause. Insulin oedema is more likely to occur in patients with a low BMI and those ...
Vitamin D deficiency predisposes individuals to type 1 and type 2 diabetes, and receptors for its activated form—1α,25-dihydroxyvitamin D 3 —have been identified in both beta cells and immune cells. Vitamin D deficiency has been shown to impair insulin synthesis and secretion in humans and ...
Vitamin D preserved insulin-producing cells and cell function, which can reduce complications in young patients. Taking a high-dose vitamin D supplement may improve the function of insulin-producing beta cells in children and young ...
vitamin-D system, in particular its potential effects on inflammatory and autoimmune conditions as well as on insulin secretion and possibly also on insulin resistance, increased the interest in its potential role in prevention and control of the diabetic condition, both type-1 and -2 diabetes. Bo...
. These were unusually concentrated near a number of genes associated with susceptibility to autoimmune conditions and to certain cancers. They also found that vitamin D had a significant effect on the activity of 229 genes including PTPN2, associated with Crohn’s disease and type 1 diabetes....
Adding a safe, inexpensive and easy to administer form of vitamin D to treatment for children newly diagnosed with type 1 diabetes shows promise to improve measures of disease progression. Results of a randomized clinical trial comparing ergocalciferol supplementation to placebo, conducted by Benjamin ...