Select stone formers may be at increased risk for recurrence with vitamin D supplementation, possibly from CYP24A1 gene mutations. Additionally, the evidence for who is vitamin D deficient, and the benefits of supplementation in those not at risk for rickets, is sparse. Concerns may be ...
An analysis of GrassrootsHealth data for 2,012 participants followed prospectively for a median of 19 months has shown no link between serum 25-hydroxyvitamin D levels of 20–100 ng/ml and kidney stones. Vitamin D levels of 40–60 ng/ml have been shown, in previous studies, to reduce the...
In the 10 trials that reported incidence of kidney stones, there was only 1 case.26,27Response to Public Comment A draft version of this recommendation statement was posted for public comment on the USPSTF website from September 22, 2020, to October 19, 2020. Some comments requested the ...
Relationship between remnant cholesterol and risk of kidney stones in U.S. adults: a 2007–2016 NHANES analysis. Ann Med. 2024;56(1):2319749. Article PubMed PubMed Central Google Scholar von Eckardstein A, Nordestgaard BG, Remaley AT, Catapano AL. High-density lipoprotein revisited: ...
It is noteworthy, however, that the combined use of vitamin D and calcium may increase the risk of kidney stones and potentially promote vascular calcification, necessitating further exploration of the efficacy of single versus combined use [50, 51]. More studies are needed in the future to ...
BACKGROUND: Concern has been raised that high levels of ascorbic acid consumption may lead to potential adverse effects, such as vitamin B12 deficiency, iron overload, and kidney stones. OBJECTIVE: To examine the relation of serum ascorbic acid level, which reflects intake, to serum vitamin B12...
62. A modestly increased risk of kidney stones was observed in the WHI trial109, but this effect was not seen in the more recent 2017–2020 megatrials (that is, ViDA, VITAL and D2d; Table1). Furthermore, no changes in kidney function were found in these large trials. Skeletal ...
Very high vitamin D levels in the blood exceeding 375 nmol/L or 150 ng/mL are toxic, potentially causing side effects such as loss of appetite, nausea, vomiting, muscle weakness, confusion, dehydration, excessive thirst, and kidney stones.[7] Extremely high blood levels of vitamin D can eve...
Vitamin D3 is preferred because it absorbs better than D2. And yes, taking too much, like more than 4,000 IU a day, can cause problems such as nausea, weight loss, constipation, confusion, and kidney stones. Dr. Mallika is offering her best advice, but as always, consult your person...
In this review, we analyzed and discussed available literature on the effect of calcium and vitamin D supplementation on the risk for kidney stone formation. Keywords: kidney stones; calcium; vitamin D 1. Introduction Kidney stone disease is characterized by high prevalence and progressively ...