Vitamin D and molecular actions on the immune system: modulation of innate and autoimmunity. J Mol Med (Berl) [Internet]. 2010 [cited 2015 Sep 2];88(5):441–50. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2861286&tool=pmcentrez&rendertype=abstract...
Immunohistochemical detection and distribution of the 1,25-dihydroxyvitamin D3 receptor in rat reproductive tissues. Histochem. Cell Biol. 105, 7–15 (1996). Article CAS PubMed Google Scholar Mahmoudi, A. R. et al. Distribution of vitamin D receptor and 1α-hydroxylase in male mouse ...
The classical functions of vitamin D are to regulate calcium-phosphorus homeostasis and control bone metabolism. However, vitamin D deficiency has been reported in several chronic conditions associated with increased inflammation and deregulation of the immune system, such as diabetes, asthma, and rheumat...
1,25-dihydroxyvitamin D3 induces nitric oxide synthase and suppresses growth of Mycobacterium tuberculosis in a human macrophage-like cell line. Infect Immun. 1998;66:5314–21. CAS PubMed PubMed Central Google Scholar Jeffery LE, Wood AM, Qureshi OS, Hou TZ, Gardner D, Briggs Z, et al....
Most cells of the immune system express the VDR[6]. It enables macrophages to respond to and kill bacterial and viral organisms. In line with this is the observation of impaired macrophage function in VDR knock-out mice[6]. Vitamin D also exerts an influence on epidermal keratinocytes to ...
To review potential benefits of vitamin D supplementation in critically ill patients.The data were collected by searching Scopus, PubMed/Medline, ScienceDirect, Clinical trials and Cochrane database systematic reviews. The keywords used as search terms were 'vitamin D', 'critically ill patients', '...
A literature search of relevant articles was performed on PubMed up to December 2019. Those articles that had examined the association of vitamin D-related SNPs with obesity and/or T2D were included. Two reviewers independently evaluated the eligibility for the inclusion criteria and extracted the ...
role of vitamin D in airway inflammation and in various respiratory diseases. A comprehensive search of the last five years of literature was conducted using MEDLINE and non-MEDLINE PubMed databases, Ovid MEDLINE, SCOPUS-Elsevier, and data from in vitro and in vivo experiments, including clinical...
Vitamin D/VDR signaling contributes to the genetic, environmental, immune, and microbial aspects of human diseases (e.g., inflammatory bowel disease and obesity)2,3. The humanVdrgene is the first gene identified as a vital host factor that shapes the gut microbiome at the genetic level4. In...
Vitamin D and folate deficiency are considered risk factors for schizophrenia and bipolar disorders, but it is unknown how vitamin D and folate influence the growing brain, cranium or the clinical phenotype. Serum vitamin D and folate levels are in part genetically regulated. We investigated whether...