Canadian Researchers Discover New Evidence That Vitamin D Shuts Down Cancer Cells - Waking Timesfeaturedsunlight vitamin d
1,25-(OH) 2 vitamin D 3 [1,25(OH) 2 D 3 ], the active metabolite of vitamin D, inhibits proliferation of a variety of tumor cells including prostate (reviewed in 1) as well as head and neck cancer. 1,25(OH) 2 D 3 effects are mediated by the vitamin D receptor, which is ...
Mitigation of Breast Cancer Cells' Invasiveness via Down Regulation of ETV7, Hippo, and PI3K/mTOR Pathways by Vitamin D3 Gold-Nanoparticles Metastasis in breast cancer is the major cause of death in females (about 30%). Based on our earlier observation that Vitamin D3 downregulates mTOR, we ...
Recent clinical trials suggest that vitamin D and its analogs promise to be important therapies for prostate cancer.7Experimental evidence indicates that the active form of vitamin D promotes differentiation and inhibits proliferation, invasiveness, and metastasis of human prostate cancer cells.8,9 In a...
While the mechanisms for how vitamin D influences breast cancer outcomes are not well understood, researchers believed it may be related to its role in promoting normal mammary-cell development, and inhibiting the reproduction of and promoting the death of cancer cells. ...
In MCF-7 cells, 1,25(OH) 2 D 3... E Nolan,M Donepudi,K Vanweelden,... - 《Molecular & Cellular Biochemistry》 被引量: 120发表: 1998年 Dissociation of vitamin D3 and anti-estrogen mediated growth regulation in MCF-7 breast cancer cells Our studies have identified 1,25(OH)2D3 as...
Calcitriol, the hormonal form of vitamin D, enhanced TNF-induced cytotoxicity in MCF-7 breast cancer cells. It increased the induction of caspase-3-like activity and TNF-induced caspase-independent cytotoxicity in the presence of a pan-caspase inhibitor. The antioxidants N-acetylcysteine, glutathione...
Cancer cells need a large supply of the vitamin to maitain their rapid growth, so they have many folic acid receptors on their membranes. Breast, kidney, lung, and several other types of cancer cells are particularly rich in these receptors. 相关知识点: 试题来源: 解析 癌细胞需要大量维生素...
Vitamin D causes early death of cancer cells. A study published in the American Journey of Clinical Nutrition reported that women who supplemented their diets with 1,000 international. Units of vitamin D every day had a 60 percent to 77 percent lower incidence of cancer ever a four-year perio...
However, it is also highly likely that vitamin D’s well-described epigenetic control of transcription in cancer cells via histone acetylation, promoter methylation or via miRNAs is also prominent in brain though this remains virtually unexplored. Given clear and consistent effects of DVD- and AVD ...