Vitamin D metabolism and bone mineralization in children with juvenile rheumatoid arthritis. J Pediatr 1994;124:910-6.Hillman L, Cassidy JT, Johnson L, Lee D, Allen SH. Vitamin D metabolism and bone mineralization in children with juvenile rheumatoid arthritis. J Pediatr 1994; 124: 910-916, ...
Vitamin D Metabolites and Bone Mineralization in Man*Vitamin D Metabolites and Bone Mineralization in Man*A comparison was made of the biochemical and osseous effects of 25-hydroxyvitamin D3 [25(OH)D3], 1 alpha-25-hydroxyvitamin D3 [1 alpha, 25(OH)2D3], and 24,25-dihydroxyvitamin D3 [...
Subsequently, mineralization disorders, as well as risk factors, are discussed. This is followed by the relationship between vitamin D deficiency, osteoporosis, and fractures. The pathophysiology and the prevention of bone loss and fractures will be discussed. Subsequently the implications for public ...
D. J. Baylink,M Stauffer,J. E. Wergedal,C Rich 摘要: Quantitative histologic methods have been devised to measure several processes dealing with formation and mineralization of matrix and bone resorption. In vitamin D-deficient rats, the total osteoblastic matrix formation rate was 20% less and...
Vitamin D3 deficiency is a highly prevalent condition worldwide. Clinically, vitamin D3 has a key role in calcium homeostasis and bone mineralization and has recently been implicated in the pathogenesis and/or progression of several acute and chronic illnesses, including cardiovascular disease (CVD)....
We conclude that vitamin D supplementation did not have a beneficial effect on skeletal mineralization in girls who were more than 2 years post menarcheal. However, there was a significant positive effect of the intervention on size adjusted total body and lumbar spine bone mineral content and a...
Although it is well established that a decrease in bone mass increases the risk of osteoporotic fractures, the proportion of fractures attributable to areal bone mineral density (BMD) is rather low. Here, we have identified bone mineralization defects together with low serum 25-hydroxyvitamin D (25...
(characterized by hypocalcemia, hyperparathyroidism, and decreased bone mineralization), indicating the importance of CYP27B1 for the maintenance of calcium homeostasis.1325-Hydroxyvitamin D3 24hydroxylase (CYP24A1) is the enzyme responsible for the catabolism of 1,25(OH)2D.14,15Direct evidence for ...
Juvenile idiopathic arthritis patients and their skeletal status: possible role of vitamin D receptor gene polymorphism We evaluated bone mineralization and metabolism changes related to vitamin D receptor (VDR) polymorphic genotypes in children with juvenile idiopathic arth... MM Kostik,AM Smirnov,GS ...
Bone Mineralization Vitamin D is vital for the proper mineralization of bones. It helpsin depositingcalcium and phosphorus into the bone matrix, strengthening bone structure. Regulation of Bone Remodeling Vitamin D influences the activity of osteoblasts and osteoclasts...